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A Comparison of the Cytotoxic Effects of Clostridium Difficile Toxins A and B on Peripheral Blood Monocytes and Intestinal Macrophages

Rini Bhavik Shah , Rini Bhavik Shah , Adrian Robins , Yash Mahida

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New Indian Journal of Surgery 3(3):p 133-133, July - September 2012. | DOI:

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Abstract

  Clostridium difficile associated colitis is mediated by its toxins A and B and results in recruitment of immune cells to the intestinal mucosa. Subsets of immune cells have previously been shown to be differentially susceptible to toxin A. However, there is little research on their interactions with toxin B.

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