Background: Congenital anomalies of urinary system are common and
are found in 3-4% of population, and 10% of terminations of pregnancies
are attributable to lethal urinary anomalies. Although timely detection of
nonlethal anomalies depends on many aspects, for instance equipment
quality, sonologist experience and timing of the ultrasound examination.
However, to confirm the findings and to attain definite diagnosis, a fetal
autopsy after the termination of a pregnancy is of utmost important and is
also crucial for genetic counseling.In view of this, the present study aimed to
determine the frequency and to identify the types of the urinary anomalies
in perinatal autopsies.
Methods: This study includes 391 perinatal autopsies conducted
prospectively from July 2016 to June 2018 at M. R. Medical College,
Basaveshwar Teaching and General Hospital, Kalaburagi. After obtaining the
consent from either parent, each fetus was examined as per the predetermined
protocol which included ultrasound diagnosis, photographs, external and
internal examination.
Results: The gestational age ranged from 16weeks to 44weeks and the mean
weight was 1123.96gm. Out of 391 cases urinary anomalies encountered in
19 cases (4.9%). Out of 19 cases, anomalies of renal parenchyma were seen
in 15 cases (78.9%) and anomalies of pelvi-ureters and bladder was seen
in 4 cases (21.1%). Three cases of urinary anomalies were associated with
syndromes and 8 cases were associated with other system anomalies.
Conclusion: The perinatal autopsy after termination of pregnancy is essential
to confirm the ultrasound findings and to make a definitive diagnosis.
Original Article
English
P. 347-354