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Utility of CBNAAT in Diagnosis of Pulmonary and Extrapulmonary Tuberculosis in (GMC Doda) India

Nazia Tabassum , Sameera Akhtar1 , Nazia Tabassum2 , Shazia Tabassum3 , Sumat–ul–Khurshid4 , Arif Rashid5

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Indian Journal of Pathology: Research and Practice 9(2 (Part-1)):p 99-102, May-August 2020. | DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9220.17

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Sameera Akhtar, Nazia Tabassum, Shazia Tabassum, Sumat–ul–Khurshid, Arif Rashid. Utility of CBNAAT in Diagnosis of Pulmonary and Extrapulmonary Tuberculosis in (GMC Doda) India. Indian J Pathol Res Pract 2020;9(2 Part I):99–102.
 

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Abstract

Background: Tuberculosis is the ninth leading cause of death worldwide. India contributes to about one fifth of global TB burden. It is very important to diagnose early and treat Tuberculosis to cut down transmission of Tuberculosis. The sensitivity of smear microscopy and its inability to detect drug resistance limits its impact on TB control. We compared the cartridge-based nucleic acid amplification test (CBNAAT) results for diagnosis of pulmonary and extra pulmonary tuberculosis with the conventional methods like sputum smear. Material and Methods: We conducted a retrospective study in department of Microbiology to analyze the utility and yield of CBNAAT from Jan 2017 to December 2017. We included all patients who were subjected to CBNAAT
in the study period. Data was collected from DOTS centre and CBNAAT centre. We collected total number of samples tested for CBNAAT, indication for CBNAAT, result of smear microscopy for AFB and CBNAAT. The study population included all the pulmonary and extra pulmonary presumptive TB cases who were subjected for further
investigations. Conclusion: CBNAAT is one of the rapid diagnostic tests available in the country and it should be routinely used under the public and private health sector effectively to detect a tuberculosis case.

Keywords: Cartridge-based nucleic acid amplification test (CBNAAT); Tuberculosis; Sputum smear; AFB; Sensitivity; Specificity.
 

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Sameera Akhtar, Nazia Tabassum, Shazia Tabassum, Sumat–ul–Khurshid, Arif Rashid. Utility of CBNAAT in Diagnosis of Pulmonary and Extrapulmonary Tuberculosis in (GMC Doda) India. Indian J Pathol Res Pract 2020;9(2 Part I):99–102.
 

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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9220.17

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