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Treatment of Tetanus-An Open Study to Compare the Efficacy of Penicillin and I.V. Metronidazole

Singhvi Inder Chand , Singhvi Inder Chand

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New Indian Journal of Surgery 7(1):p 67-70, January - April 2016. | DOI: DOI: https://dx.doi.org/10.21088/nijs.0976.4747.7116.15

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Abstract

 Introduction: During the past decade metronidazole has emerged as highly effective agent, both for treating and preventing a wide variety of anerobic bacterial disease. It is a stable and readily available drug that rapidly achieves theraputic concentration in virtually all body tissue and fluids after rectal, oral and intravenous administration. Methodology: This work essentially consists of management of tetanus cases admitted to Government General Hospital  and compare the results of cases treeated with I.V. Metronidazole and pencillin Results: In penicillin group 90% deaths occurred whereas in Metronidazole group 47% deaths occurred among severe cases. In penicillin group  30% deaths occurred whereas in  Metronidazole group  28% deaths occurred among mild cases. Conclusion: Duration of stay in hospital in metronidazole group is shorter compared to penicillin group.

Keywords: Tetanus; Metronidazole; Penicillin.

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DOI: DOI: https://dx.doi.org/10.21088/nijs.0976.4747.7116.15

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