Abstract

Background: Gallstone disease is a global health problem with multifactorial etiology. In recent years, Helicobacter pylori has been suggested as a possible contributor to gallstone pathogenesis. This study investigates the association between H. pylori infection and gallstone disease in patients undergoing cholecystectomy. Findings demonstrate a significant correlation, suggesting that H. pylori may act as an additional risk factor for gallstone formation.

Objective: To investigate the association between Helicobacter pylori infection and gallstone disease by detecting the presence of H. pylori in gallbladder tissue of patients undergoing cholecystectomy, and to evaluate its potential role as a risk factor in gallstone pathogenesis.

Methods: This was a prospective observational study conducted at the Department of General Surgery, Sardar Patel Medical College, Bikaner. Patients admitted with gallstone disease who underwent elective or emergency cholecystectomy were included for Giemsa staining

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