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Indian Journal of Obstetrics and Gynecology

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The Effect of Hyoscine Butylbromide and Drotaverin on First Stage of Labor

Sreelatha S., Associate Professor, Department of Obstetrics and Gynaecology, ESI Post Graduate Institute of Medical Science and Research, Rajajinagar, Bengaluru, Karnataka 560010, India. , Harshini V.* , Sreelatha S.** , Ramya S.*** , Shweta Sharan*** , Praneetha K.***

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Indian Journal of Obstetrics and Gynecology 5(3):p 413-416, Jul-Sep 2017. | DOI: http://dx.doi.org/10.21088/ijog.2321.1636.5317.17

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Abstract

Active management of labor is a part and parcel of modern obstetrics. Various drugs have been tried to hasten cervical dilatation so that problems and hazards of prolonged labor both for the mother and fetus are minimized without increasing maternal or perinatal mortality and morbidity. To compare the effect of drotavarin versus hyoscine on shortening duration of 1st stage of labor is assessed. Methods: A prospective study conducted in Department of Obstetrics and Gynecology, ESIMC PGI MSR Bangalore, Karnataka. Data collected from One Hundred pregnant women in active labor, labor accelerated using drotaverin and hysocin , duration of labor was compared among groups. Result: The two groups Group A using hyoscine butylbromide, Group B using Drotaverin, were compared with regards to rate dilatation of cervix and duration of first stage labor. Average time to full cervical dilatation was significantly less in Group B in both nulliparas and in multipara. Similarly, the average rate of cervical dilatation was significantly more in Group a, both in nulliparas and in multipara. Conclusion: Hyoscine butylbromide is more efficacious than drotaverine hydrochloride for cervical dilatation and reducing duration of active phase of 1st stage of labor.

Keywords: Hyoscine Butylbromide; Drotaverin; Duration of 1st Stage; Cervical Dialation; Labor Augmentation. 

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DOI: http://dx.doi.org/10.21088/ijog.2321.1636.5317.17

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