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Tear Film Abnormalities in Pateints with Pseudoexfoliation Syndrome

Ramya Deepthi P., Assistant Professor, Department of Ophthalmology, Narayana Medical College and Hospitals, Nellore, Andhra Pradesh 524003, India. , Kumar Amruth C1 , Ramya Deepthi P2 , Shiva Krishna M3

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Ophthalmology and Allied Sciences 4(3):p 201-204, Sep-Dec 2018. | DOI: DOI: http://dx.doi.org/10.21088/oas.2454.7816.4318.2

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Aim: The present study is designed to understand the tear film abnormalities in patients with pseudoexfoliation syndrome. Method: The prospective non-randomized study of 50 eyes of 25 normal subjects and 50 eyes of 35 patients with PEX syndrome were undertaken. Tear film changes, schirmer’s 2 test and tear film break up time (TBUT) were performed. Result: The mean age was 56.4±4.2 years and 60.27±5.3 years in both PEX and control group respectively. 20 (57.1%) of the 35 patients in the study group had unilateral PEX and other 15 (42.85%) had bilateral presentation. The average mydriasis in eyes with PEX syndrome was 5.2 mm and in eyes without PEX syndrome was 6.5mm. Average Schirmer’s and TBUT in control group were 18.15±4.2 mm and 14.75±2.5s respectively. Whereas, the values were 7.21± 3.4 mm and 6.2±2.1s in PEX group and the differences were statistically significant (p< 0.05). Conclusion: Analysis of tear functions can help in the better management of PEX syndrome. 

Keywords: PEX Syndrome; Tear Film Break Up Time (Tbut); Schirmer’s 2 Test.

 

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DOI: DOI: http://dx.doi.org/10.21088/oas.2454.7816.4318.2

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