Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Synergestic Effect between Dexmedetomidine and 0.75% Ropivacaine in Epidural

Punidha Vardhani R., Assistant Professor, Dept. of Anesthesia, Government Stanley Medical College and Hospital, Chennai, Tamil Nadu 600001, India. , Rajaram J.1 , Punidha Vardhani R.2

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 5(9):p 1541-1547, September 2018. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5918.18

How Cite This Article:

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Objective: The aim of this study is to evaluate and compare the clinical effects of added dexmedetomidine to epidural ropivacaine 0.75% for lower limb orthopedic procedures.

Methods: 40 patients undergoing elective lower limb orthopedic procedures under epidural anesthesia were selected and divided into two groups of 20 each and assigned into Control Group (N=20): Epidural ropivacaine 0.75% 20ml (150mg)+1ml NS, Dexmedetomidine Group (N=20): Epidural ropivacaine 0.75% 20ml (150mg)+ Dexmedetomidine 1g/kg+NS to complete 1ml. Variables studied include: Block onset time, maximum dermatomal level of anesthesia, duration of sensory and motor blockade, motor block intensityassessed by bromage motor scale, sensory block assessed by sensory scale, level of sedation assessed by ramsay sedation scale, hemodynamics, duration post operative analgesiavas score

Results: Duration of analgesia was prolonged in Dex group, level of significance (p<0.05), Motor block duration was prolonged in Dex group, level of significance (p<0.05), Intensity of motor block slightly increased in dex group, but without significance (p<0.37), need for Supplemental sedation was reduced need in Dex group, level of significance (p<0.05), Duration of post-op analgesia was significantly prolonged in Dex group when compared to control group, level of significance (p<0.001).

Conclusion: There was a clear synergism between epidural dexmedetomidine and ropivacaine. Dexmedetomidine increases sensory and motor block duration during epidural anesthesia with ropivacaine, prolongs postoperative analgesia and does not cause hemodynamic instability.


 

References

No records found.


About this article

Cite this article

Licence:



Received Accepted Published
N/A N/A N/A
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5918.18

Keywords

Synergestic Effect Between Dexmedetomidine and 0.75% Ropivacaine in Epidural.

Article Level Metrics

Last Updated

Monday 13 July 2026, 05:15:40 (IST)

5647

Accesses

7
678
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share