Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Comparison of Efficacy of 0.25% Bupivacaine and 0.25% BupivacaineClonidine Combination in Ultrasound Guided Transversus Abdominis Plane Block

Pradeep Karunagaran, Assistant Professor, Department of Anaesthesiology, Saveetha Medical College Hospital, Thandalam, Kanchipuram district, Tamilnadu 602105, India. , Balasubramanian Sreelatha1 , Karunagaran Pradeep2 , Dhanasekaran Ramkumar3

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 5(9):p 1536-1540, September 2018. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5918.17

How Cite This Article:

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Background and Aims: Pain is the most common symptom seen postoperatively and multiple approaches are used to overcome it. In this study, we compared bupivacaine and bupivacaine – clonidine combination in transversus abdominis plane (TAP) block for postoperative analgesia in patients undergoing inguinal hernioplasty under spinal anaesthesia.

Methods: Sixty ASA I and II male patients in the age group of 18 to 60 years posted for inguinal hernioplasty were randomly divided into two groups (Group B and Group C). The procedure was done under spinal anaesthesia using 3 ml of 0.5% hyperbaric bupivacaine. After the surgery, ultrasound guided TAP block was given with 19.5 ml of 0.25% bupivacaine + 0.5 ml sterile water in Group B and 19.5 ml of 0.25% bupivacaine + 75 mcg of clonidine (0.5 ml) in Group C. Postoperatively, the patients’ haemodynamic status, visual analogue scale (VAS) scores, dose of rescue analgesic used, duration of analgesia were recorded. Inj. Tramadol 100 mg was given intravenously as rescue analgesic when the VAS score was more than four. Data were analyzed using unpaired t test and Mann- Whitney test wherever indicated.

Results: The heart rates recorded at 6, 8, 10, 12 and 14 hours after TAP block were significantly lower in Group C compared to Group B (p< 0.05). The heart rates recorded at 16 and18 hours after TAP block were significantly lower in Group B compared to Group C. The mean arterial pressures (MAP) and VAS scores recorded at 6 and 8 hours after TAP block were significantly lower in Group C compared to Group B. The mean dose of tramadol administered was significantly lower in Group 96.67±18.25 mg) compared to Group B (186.67±34.57 mg) (p value 0.0001). The mean duration of analgesia was significantly higher in Group C (943.46±70.751 minutes) compared to Group B (413.20±45.023 minutes, p value 0.001).

Conclusion: Addition of clonidine to 0.25% bupivacaine for TAP block significantly prolongs the duration of analgesia and reduces postoperative analgesic requirements compared to patients receiving 0.25% bupivacaine alone.

 

References

No records found.


About this article

Cite this article

Licence:



Received Accepted Published
N/A N/A N/A
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.5918.17

Keywords

Bupivacaine; Clonidine; Inguinal Hernioplasty; Transversus Abdominis Plane (TAP) Block.

Article Level Metrics

Last Updated

Saturday 28 February 2026, 17:56:51 (IST)

1391

Accesses

0
246
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share