Home > Journals > Indian Journal of Pathology: Research and Practice

Indian Journal of Pathology: Research and Practice

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Study on Spectrum of Neuroendocrine Neoplasms of Digestive System

Gauri Kelkar , Nivedita SB1 , Gauri Kelkar2

Author Information

Licence:



Indian Journal of Pathology: Research and Practice 8(5):p 620-631, September-October 2019. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8519.16

How Cite This Article:

Nivedita SB, Gauri Kelkar. Study on Spectrum of Neuroendocrine Neoplasms of Digestive System. Indian J Pathol Res Pract. 2019;8(5):620–631.
 

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Background: According to the survey data from the Surveillance, Epidemiology, and End Results (SEER) program, the incidence of malignant GI-NETs is increasing, probably due to increased physician awareness and improved diagnostic techniques. The present study was undertaken to study on occurrence and spectrum of neuroendocrine neoplasms in the digestive system. Method: This hospital-based study was conducted at the Kidwai Memorial Institute of Oncology, Bangalore. The present study consists of 118 cases of Digestive System NENs encountered during a 10 year study period. Retrospective cases were retrieved from the registers of Histopathology and Immuno histochemistry divisions and slides were analyzed. For the prospective study, complete clinical data was obtained from the patient and clinical records. Data regarding routine laboratory investigations, abdominal ultrasound, CT Scan, MRI, upper or lower GI endoscopy and peroperative findings, medical treatment and follow up data were analyzed. Result: Oesophagus was the most common site (35%), followed by the stomach (23%), small intestine (22.0%), large intestine (6.%), rectum (7%), pancreas (4.2%), one case each of appendix, gall bladder, common bile duct and metastasis to the liver. In the oesophagus, NEC was the most common diagnosis. G1 NETs were the most common NENs of the stomach, small intestine and pancreas. G2 NETs were most common in the large intestine, gall bladder, CBD, rectum & liver metastasis. Conclusion: The incidence of neoplasms is increasing because of early diagnosis by use of modern diagnostic methods and better physician awareness. Use of WHO 2010 classification helps in the classification of NENs and grading will impact the treatment and prognosis of individual patients.

Keywords: Neuroendocrine neoplasms; Digestive system; Immunohistochemistry; WHO classification.

References

No records found.


About this article

Cite this article

Nivedita SB, Gauri Kelkar. Study on Spectrum of Neuroendocrine Neoplasms of Digestive System. Indian J Pathol Res Pract. 2019;8(5):620–631.
 

Licence:



Received Accepted Published
N/A N/A N/A
DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8519.16

Keywords


Article Level Metrics

Last Updated

Sunday 12 July 2026, 14:53:33 (IST)

2018

Accesses

2
434
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share