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Study Article on Various Etiologies of Thrombocytopenia in Adults in a Tertiary Care Centre in South Gujarat

Toral Jivani , Akruti Patel1 , Toral Jivani2 , Purvi Patel3

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Indian Journal of Pathology: Research and Practice 9(1 (Part-I)):p 9-14, January-April 2020. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9120.1

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Akruti Patel, Toral Jivani, Purvi Patel. Study Article on Various Etiologies of Thrombocytopenia in Adults in a Tertiary Care Centre in South Gujarat. Indian J Pathol Res Pract. 2020;9(1):9–14.

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Abstract

Introduction: Thrombocytopenia is a common hematological abnormality observed in hospitalized patients. It is defined as platelet count of less than 150 × 103 per µL. There are various mechanisms like: due to deficient production of platelets, destruction of platelets-both immune or non-immune mediated or due to combination of both. Aims and objective: This study was carried out to find various etiologies of thrombocytopenia. Methods: The prospective study was carried out on 100 patients admitted at SMIMER Hospital in the month of April–June, 2019 and on the basis of their data, platelet count, age distribution, gender and etiology of thrombocytopenia have been studied. Result: Thrombocytopenia is more common in younger age group of patients that is between 21 and 30 years (34/100 patients) with the maximum patients having platelet count between 50,000 and 1,00,000 per µL (48/100 patients). It is more common amongst the male patients (65/100 patients). The most common infective etiology is Plasmodium vivax infection (52%) and non-infective etiology is Megaloblastic Anemia (27%). Conclusion: Thrombocytopenia is usually associated with various etiologies but most common amongst them is infective etiology. Hence, for proper management of the patient, the specific cause should be found out.

Keywords: Thrombocytopenia; P.vivax; Megaloblastic anemia.

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Akruti Patel, Toral Jivani, Purvi Patel. Study Article on Various Etiologies of Thrombocytopenia in Adults in a Tertiary Care Centre in South Gujarat. Indian J Pathol Res Pract. 2020;9(1):9–14.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9120.1

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