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Indian Journal of Pathology: Research and Practice

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Spectrum of Various Causes of Pancytopenia in a Tertiary Care Hospital

Megha Agrawal, Assistant Professor, Department of Pathology, Integral Institute of Medical Sciences & Research, Lucknow, Uttar Pradesh 226026, India , Javed Iqbal1 , Megha Agrawal2 , Nausheen Khan3 , Sidhartha Shankar Sinha4

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Indian Journal of Pathology: Research and Practice 7(9):p 995-998, September 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7918.7

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Abstract

Objective: Bone marrow examination performed in cases of pancytopenia detected on peripheral blood smears to find out cause of it. Place & duration: The study was carried out at Integral Institute of Medical Sciences & Research, Lucknow from Jan 2017-June 2018. Material & Methods: We report 43 cases of pancytopenia.Bone marrow aspiration was done by 16 gauze salah needle and obtained smears then stained with leishman and MGG stain. Results: Out of 43 cases, 28 were males and 15 were females. 29 smears shows of hypercellular marrow, hypocellular smears in 8 cases & 6 cases were of normocellular marrow. Conclusion: This study conclude that the megaloblastic anemia was the common etiology. Other causes are acute leukemias, nutritional anemia with dual deficiency & multiple myeloma.

 
Keywords: Pancytopenia; Megaloblastic Anemia

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7918.7

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