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Indian Journal of Maternal-Fetal & Neonatal Medicine 12(2):p 51-56, July- Dec. 2025. | DOI: 10.21088/ijmfnm.2455.8621.12225.3
Review Article
Role of Mifepristone in Obstetrics and Gynecology and Endocrinology
Prachi Vilas Saner, Harshali Rajiv Tuknait, Amruta Suhas Patil, Sanskruti R Rathod
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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Indian Journal of Maternal-Fetal & Neonatal Medicine 12(2):p 51-56, July- Dec. 2025. | DOI: 10.21088/ijmfnm.2455.8621.12225.3
How Cite This Article:
Jaiswal S. The Role of Artificial Intellect and Machine Learning in Techniques for Assisted Fertility. Indian Journal of Maternal-Fetal & Neonatal Medicine. 2025;12(2):45-50.Timeline
Received : June 11, 2025
Accepted : July 21, 2025
Published : December 30, 2025
Abstract
Mifepristone, a synthetic steroid with potent antiprogestational and antiglucocorticoid activity, has established itself as a versatile pharmacological agent with significant clinical implications. Initially approved for medical termination of early pregnancy, mifepristone functions by competitively inhibiting progesterone receptors, disrupting endometrial support and promoting uterine contractility when used alongside prostaglandins. Its clinical utility, however, extends well beyond reproductive health. It is employed in cervical ripening, second-trimester abortion, and labor induction.Furthermore, mifepristone has demonstrated therapeutic potential in the management of uterine fibroids, endometriosis, and as a targeted treatment in Cushing’s syndrome by modulating glucocorticoid receptors. Emerging research also explores its role in treating hormone-sensitive malignancies, including breast and ovarian cancers. As evidence continues to grow, mifepristone represents a promising tool in both gynecological and endocrine therapy, warranting further exploration and integration into broader clinical practice.
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Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
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Cite this article
Jaiswal S. The Role of Artificial Intellect and Machine Learning in Techniques for Assisted Fertility. Indian Journal of Maternal-Fetal & Neonatal Medicine. 2025;12(2):45-50.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| June 11, 2025 | July 21, 2025 | December 30, 2025 |
DOI: 10.21088/ijmfnm.2455.8621.12225.3
Keywords
MifepristoneMedical abortionEmergency contraceptionFibroidArticle Level Metrics
Last UpdatedWednesday 17 June 2026, 08:44:18 (IST)
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Timeline
| Received | June 11, 2025 |
| Accepted | July 21, 2025 |
| Published | December 30, 2025 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
