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Role of Functional Regenerative Four Layered Scaffold Dressing in Wound Bed Preparation

Ravi Kumar Chittoria, Kanav Gupta, Prabin Mandal

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Journal of Global Medical Education and Research 8(2):p 71-74, July -Dec. 2025. | DOI: n.a

How Cite This Article:

Gupta K, Chittoria RK, Mandal P. Role of Functional Regenerative Four Layered Scaffold Dressing in Wound Bed Preparation. Jr of Glob Med Edu and Res. 2025;8(2):71–4.

Timeline

Received : July 07, 2025         Accepted : September 27, 2025          Published : December 31, 2025

Abstract

The understanding of wound healing has led to the inclusion of tissue regeneration therapy as an armamentarium to deal with both acute and chronic wounds. The bio constructs that aid in wound regeneration was made using natural, artificial, or a combination of both, widely known as regeneration scaffolds. The components of regeneration scaffolds promote the inherent self-renewal property of the skin and speed up the healing process by providing growth factors/stem cells. The scaffolds are in use for so many years. But the commercially available scaffolds are very expensive. Hence an indigenous scaffold was made use of multiple components like amniotic membrane, collagen, and silicone. Which was found to be in no way inferior to any of the commercially available scaffolds.


References

  • 1.   Burke, J.F. et al. (1981) Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury. Ann. Surg. 194, 413-428.
  • 2.   Jones, I. et al. (2002) A guide to biological skin substitutes. Br. J. Plast. Surg. 55, 185-193.
  • 3.   Chevallay, B. and Herbage, D. (2000) Collagenbased biomaterials as 3D scaffold for cell cultures: Applications for tissue engineering and gene therapy. Med. Biol. Eng. Comput. 38, 211-218.
  • 4.   Kim, B.S. and Mooney, D.J. (1998) Development of biocompatible synthetic extracellular matrices for tissue engineering. Trends Biotechnol. 16, 224-230.
  • 5.   Kannan, R.Y. et al. (2007) Silsesquioxane nanocomposites as tissue implants. Plast. Reconstr. Surg. 119, 1653-1662.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Gupta K, Chittoria RK, Mandal P. Role of Functional Regenerative Four Layered Scaffold Dressing in Wound Bed Preparation. Jr of Glob Med Edu and Res. 2025;8(2):71–4.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



Received Accepted Published
July 07, 2025 September 27, 2025 December 31, 2025

DOI: n.a

Keywords

Regeneration ScaffoldPost Burn Raw areaDermal RegenerationRegenerative Therapy: Amniotic membrane

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Received July 07, 2025
Accepted September 27, 2025
Published December 31, 2025

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



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