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Retrospective Analysis of Coagulation Profile in Pregnancy Induced Hypertension Cases in a Tertiary Care Hospital

B. Syam Sundar, Associate Professor, Department of Pathology, Narayana Medical College, Chintareddy Palem, Nellore, Andhra Pradesh 524003, India. , Byna Syam Sundara Rao* , Nandam Mohan Rao* , Vissa Shanthi** , Bhavana Grandhi*** , Vijayalakshmi Muram Reddy*** , Kumar Chinta****

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Indian Journal of Pathology: Research and Practice 6(3(part-2)):p 734-739, Jul-Sep 2017. | DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6317.39

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Abstract

Background: It is a physiological process in women and is associated with risk to health of both mother and child. To prevent maternal and fetal morbidity and mortality by early assessment of severity of pre eclampsia and eclampsia. Objective: to compare the coagulation parameters between the test group and control group. Materials and Methods: A total number of 30 normal antenatal women without Pregnancy induced hypertension are included in control group and a total number of cases of Pregnancy induced hypertension are taken as test group. Comparision of coagulation parameters like Activated partial thromboplastin time, Prothrombin time and platelet count were studied in these patients. This study was undertaken for a period of one year of January 2016 to January 2017 in department of pathology, central laboratory, narayana medical college & hospital, Nellore. Results: Coagulation parameters such as Activated partial thromboplastin time, Prothrombin time and platelet count were studied in both 30 control and cases. Study showed significant alteration of coagulation profile depending on severity of disease. All results were statistically analysed. Conclusion: Estimation of different parameters like Activated partial thromboplastin time, Prothrombin time and platelet count play s a role in the diagnosis of Pregnancy induced hypertension and evaluation of risk factors, early detection of which will decrease maternal morbidity and mortality.

Keyords: Pregnancy Induced Hypertension; Preeclampsia; Activated Partial Thromboplastin Time; Prothrombin Time; Platelet Count. 

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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6317.39

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