Vaishali Taralekar Professor, Department of Obstetric and Gynaecology, Bharati Vidyapeeth, Hospital and Medical College, Pune- 416414, Maharashtra, India
Vishal Mali Junior Resident (Jr-3), epartment of Obstetric and Gynaecology, Bharati Vidyapeeth, Hospital and Medical College, Pune-416414, Maharashtra, India
Suchita Dabhadkar Associate Professor, Department of Obstetric and Gynaecology, Bharati Vidyapeeth, Hospital and Medical College, Pune-416414, Maharashtra, India
Address for correspondence: Vaishali Taralekar, Professor, Department of Obstetric and Gynaecology, Bharati Vidyapeeth, Hospital and Medical College, Pune- 416414, Maharashtra, India E-mail: vishalmali9071@gmail.com
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Vishal Mali, Vaishali Taralekar, Suchita Dabhadkar/Prospective Observational study of Etiological Spectrum of Febrile Illinessess in Pregnancy and Association with Outcomes/Indian J Obstet Gynecol. 2023;11(2):63–68.
Timeline
Received : March 25, 2023
Accepted : April 20, 2023
Published : June 30, 2023
Abstract
Background:- Fever in pregnancy is a common clinical problem worldwide. The risk to the mother and fetus is significantly increased in pregnancy complicated by infection and fever. Aim and objective:- To determine etiological spectrum of febrile illnesses in pregnancy and its association with maternal & fetal outcomes. Methodology :- Prospective observational study was conducted in the Department of obstetrics and gynecology in a tertiary care center in western Maharashtra. A total 105 pregnant women reported with fever during the study periods, out of which 37 were followed up longitudinally till delivery and were included in the study analysis. Results:- In the present study, Fever of unknown origin(32.43%), Dengue(24.32%), COVID-19 (24.32%), Urinary tract infections(16.21%) Malaria(2.7%) were the common cause of febrile illness. Out of 37 pregnant women with febrile illness, 31 (83.8%) had live births, 5 (13.5%) had intrauterine death (IUD) and there was one case of abortion. In 10 (27%) patients, there was a requirement for NICU admission. It was observed that more is the number of febrile episodes higher is the chance of neonatal morbidity and mortality. Conclusion :- High grade fever with multiple febrile episodes due to any underlying etiology in pregnancy is harmful to the fetal-maternal health.
References
1. Edwards MJ. Review: Hyperthermia and fever during pregnancy. Birth Defects Res A Clin Mol Teratol. 2006 Jul;76(7):507-16. doi: 10.1002/ bdra.20277. PMID: 16933304.
2. Maharaj D. Fever in Pregnancy - Infectious Disease and Antimicrobial Agents [Internet]. Antimicrobe. org. 2017[cited 19 December 2017]. Available from: http://www.antimicrobe.org/e42.asp
3. Emergency-committee-regarding-the-outbreak-ofnovelcoronavirus-(2019-ncov) 2005. [Last accessed on 2020 Jun 20]. Available from: https://www.who. int/news-room/detail/30-01-2020-statementonth e -s e c o n d - m e e ti n go f- t h e - in te rn at i o n a l - healthregulations
4. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al.Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020;382:1708–20.10.1056/ NEJMoa2002032Search in Google Scholar
5. Kourtis AP, Read JS, Jamieson DJ. Pregnancy and infection. N Engl J Med. 2014;370:2211–8. https:// doi.org/10.1056/NEJMra1213566
6. Gluckman PD, Wyatt J, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomized trial. Lancet. 2005;365(9460):663-70. doi:10.1016/ s0140-6736(05)17946-x
7. Shahrukh Hashmi S, Gallaway MS, Waller DK, Langlois PH, Hecht JT; National Birth Defects Prevention Study. Maternal fever during early pregnancy and the risk of oral clefts. Birth Defects Res A Clin Mol Teratol. 2010 Mar;88(3):186-94
8. International journal of reproduction, contraception, obstetrics and gynecology More VS. Int J Reprod Contracept Obstet Gynecol .2017 Dec;6(12):55235527, www.ijrcog.org
9. Brar R, Suri V, Suri V, Singh MP, Biswal M, Sikka P. Fever During Pregnancy: Etiology and Fetomaternal Outcomes. J Obstet Gynaecol India. 2022 Aug;72 (Suppl 1):102-108.
10. Sultan S, Parihar R, Badkur P. Study on pyrexia in pregnancy and labour with special emphasis on fetomaternal outcome. Int J Reprod Contracept Obstet Gynecol 2020;9:4414-9.
11. Biswas, Jhuma & Banerjee, Kaushik & Sanyal, Poushali & Datta, Mousumi & Choudhury, Subhendu & Dasgupta, Shyamal & Gupta, Sayantanee & Dey, Amar. (2015). Fetomaternal Outcome of Pyrexia in Pregnancy: A Prospective Study. International Journal of Women's Health and Reproduction Sciences. 3. 132-135. 10.15296/ ijwhr.2015.28.
Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study
Conflicts of Interest
No conflicts of interest in this work.
About this article
Cite this article
Vishal Mali, Vaishali Taralekar, Suchita Dabhadkar/Prospective Observational study of Etiological Spectrum of Febrile Illinessess in Pregnancy and Association with Outcomes/Indian J Obstet Gynecol. 2023;11(2):63–68.
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.