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Prospective Histopathological Study of Neoplastic Lesions of Breast at a Tertiary Care Teaching Center

Rashmi Chandragouda Meti, Associate Professor, Department of Microbiology, Kamineni Institute of Medical Sciences, Narketpalli, Nalgonda, Telangana 508254, India. , Anand Nagalikar1 , Rashmi Chandragouda Meti2

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Indian Journal of Pathology: Research and Practice 7(5):p 674-678, May 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7518.18

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Abstract

  Background:Breast lesion is the most common malignant tumor and the leading cause of carcinoma death in women, with more than 10 lakh cases occurring worldwide annually. Benign breast lesion is a neglected entity despite the fact that it constitutes the majority of breast problems. Breast cancer has taken precedence over benign breast disease since it is more fearsome although the number of females with benign breast disease is substantial.

Materials & Methods: This study was hospital based prospective study including all the patients with breast lump who attended hospital. Comparison between cytology and histology was done according to availability of samples. Their attention was given to age, sex, laterality, non-neoplastic and neoplastic lesions. Specimen was fixed in 10% formalin saline for 24 hours, gross features will be examined, after processing tissue was embedded in paraffin wax to make block with the help of moulds. Serial Section, 3-5 micron thick were cut and these slides were kept in hot oven at 66 OC for one hour to fix the section on slides  before staining with routine Hematoxylin and Eosin.

Results: A total of 100 cases were studied over a period of 1 year,of which benign lesion constituted 82.0% of cases where as malignant cases were 18.0%.In our study, 85 were female (85.0%) and 15 were male (15.0%). All the breast lesions in male were benign lesion (gynaecomastia). Out of 100 patients with breast lesions, 56 (56.0%) had left sided
involvement, 40(40.0%) had right sided involvement whereas 4 (4.0%) had bilateral involvement.

Conclusion: In our study, benign breast diseases are more common compared to malignant diseases of breast in the ratio of 4.55: 1.Breast self-examinationand education to females are very important for early diagnosis and treatment of breast diseases. 

Keywords: Benign; Malignant; Benign Brest Disease; Histopathological

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7518.18

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