Sai Datri A Assistant Professor, Department of Pharmaceutical Analysis, Vallabhaneni Venkatadri Institute of Pharmaceutical Sciences, Gudlavalleru 521356, Andhra Pradesh, India
Lakshmana Rao A Professor and Principal, Department of Pharmaceutical Analysis, Vallabhaneni Venkatadri Institute of Pharmaceutical Sciences, Gudlavalleru 521356, Andhra Pradesh, India
Mahesh Chandra Narayana N Students, Department of Pharmaceutical Analysis, Vallabhaneni Venkatadri Institute of Pharmaceutical Sciences, Gudlavalleru 521356, Andhra Pradesh, India
Durga Bhavani P Students, Department of Pharmaceutical Analysis, Vallabhaneni Venkatadri Institute of Pharmaceutical Sciences, Gudlavalleru 521356, Andhra Pradesh, India
Yamini Padma Bhavani P Students, Department of Pharmaceutical Analysis, Vallabhaneni Venkatadri Institute of Pharmaceutical Sciences, Gudlavalleru 521356, Andhra Pradesh, India
Bhargavi P Students, Department of Pharmaceutical Analysis, Vallabhaneni Venkatadri Institute of Pharmaceutical Sciences, Gudlavalleru 521356, Andhra Pradesh, India
Meghana P Students, Department of Pharmaceutical Analysis, Vallabhaneni Venkatadri Institute of Pharmaceutical Sciences, Gudlavalleru 521356, Andhra Pradesh, India
Address for correspondence: Sai Datri A, Assistant Professor, Department of Pharmaceutical Analysis, Vallabhaneni Venkatadri Institute of Pharmaceutical Sciences, Gudlavalleru 521356, Andhra Pradesh, India E-mail: sai.dhatri_arige@yahoo.co.in
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator.
Sai Datri A, Lakshmana Rao A, Mahesh Chandra Narayana N, et al./Preparation & Evaluation of Medicated Embelia Ribes Jellies for Obese Patients/J Pharmaceut Med Chem. 2023;9(2): 61-64.
Timeline
Received : July 19, 2023
Accepted : September 01, 2023
Published : December 25, 2023
Abstract
Medicated herbal jellies are more suitable for child & old age patients, which is going to be easy administration & high absorption of drugs. This study aims to prepare such a jelly preparation that effects the LDL level in Obese patients. Due to resistance & side effects of conventional synthetic medication, herbal drug preparations are well-accepted. The Jellies are alternatives for traditional methods like ‘Churna’ and ‘Tablets’. This research is to develop a new dosage form of embelin into jellies and their pharmaceutical standardization. During the study extraction of embelin from Embeliaribes, formulation of jellies, processing procedure with extract based herbal formulation, and expansion for analytical standardization including qualitative and quantitative determinations were carried out. The formulation was subjected to physico-chemical as well as in-vitro drug release.
References
1. Sruthi S, Dr. Umesh Kumar S, Arathy S.A. Pharmaceutical Jellies: A novel way of drug delivery. Journal of Pharmaceutical Sciences and Research. 2020; 12(7): 904-909.
3. Sandeep R, Gyanranjan S, Deepayan P, Udit Nandan M and Ajay Kumar P. Embeliaribes Burm F. (Vai Vidanga)- An Overview. International Journal of Modern Agriculture. 2021; 10(2): 4588-4594.
4. Hemantkumar S.C, Uma B, Geetika K. Preventive effect of embelin from embeliaribes on lipid metabolism and oxidative stress in high-fat dietinduced obesity in rats. National Library of Medicine. 2012;78(7):651-657.
6. Barbara N.E, Luiza P.D.M, Barbara P.S, Mariana G, Haira G.L, Vinicius P.V, Susanne U.M, Carla O.B.R, and Hercia S.D.M. Chia seed (Salvia hispanica L.) effects and their molecular mechanisms on unbalanced diet experimental studies: A systematic review. Journal of Food Science. 2020; 85(2): 226- 239.
7. Rahul R, Jaiswal S, Jitendra J. Stevia as a natural sweetener. International Journal of Research in Pharmacy and Chemistry. 2011;1(4):1199-1202.
8. Pundarikakshudu K, Joshi H, Shah P, and Panchal S. A simple, facile method for isolation of embelin from fruitsof Embeliaribes Burm. f. Indian Drugs. 2016; 53(02): 23-27. 9 (10).
9. Satyanarayana D.A, Kulkarni P.K, Shivakumar G.H. Gels and jellies as a dosage form for dysphagia patients: A review. Current Drug Therapy. 2011;6:79-86.
10. Carter S.J. Cooper and Gunn’s Dispensing for Pharmaceutical Students. 12th ed. New Delhi: CBS Publishers and Distributors; 2008; 214-8.
11. Ofner III C.M, Klech-Gelotte C.M. Gels and jellies. In: Swarbrick J, editor. Encyclopedia of Pharmaceutical Technology. New York: Informa Healthcare 1980; 1875-90.
Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
About this article
Cite this article
Sai Datri A, Lakshmana Rao A, Mahesh Chandra Narayana N, et al./Preparation & Evaluation of Medicated Embelia Ribes Jellies for Obese Patients/J Pharmaceut Med Chem. 2023;9(2): 61-64.
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator.
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator.