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Case Report

Pregnancy and Antiphospholipid Antibody Syndrome

Sumanth T null, Aswin B 1 null, Sumanth T 2 null, Ravi Madhusudhana 3 null

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

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Indian Journal of Anesthesia and Analgesia 9(3):p 41-43, May-June 2022. | DOI: https://doi.org/10.21088/ijaa.2349.8471.9322.14

How Cite This Article:

Aswin B, Sumanth T, Ravi Madhusudhana/Pregnancy and Antiphospholipid Antibody Syndrome/Indian J Anesth Analg. 2022;9(3):141-143.
 

Timeline

Received : April 12, 2022         Accepted : May 03, 2022          Published : June 20, 2022

Abstract

Introduction: ALPA is an autoimmune hypercoagulable state caused by antiphospholipid antibodies. It is characterized by thrombotic episodes in arteries, veins and pregnancy related complications like still birth, preterm delivery, miscarriage and severe preeclampsia. We report a case of APLA syndrome due to its rarity. Case Report: A 28 year old woman with a history of two previous abortions and positive serology for APLAs with 9 months gestation came to our hospital for safe confinement. She was diagnosed as primary APLA syndrome in view of bad obstetric history and positive lupus anticoagulant. She is a known hypothyroidism. She was on Injection Enoxaparin 0.6 ml OD for 1 year which was changed to unfractionated heparin 14000 units OD subcutaneously after admitting to our hospital. In view of bad obstetric history, an elective caesarean section was planned. Unfractionated heparin was stopped 24 hours before surgery. Preoperative investigations revealed a normal APTT, PT, INR. Spinal anesthesia given in L3–L4 inter-spinal space with 25G needle after preloading with 500 ml crystalloids and a sensory block up to T6 was attained. She delivered a single live male child with APGAR score 9. Injection Oxytocin 15 units was given intraoperatively. The further perioperative course was uneventful. She was restarted on Injection Enoxaparin 0.6ml OD for 6 weeks. 

References

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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

Provide information related to the Ethics Committee approval with approval number OR write, This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

The authors report no conflicts of interest in this work.

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Cite this article

Aswin B, Sumanth T, Ravi Madhusudhana/Pregnancy and Antiphospholipid Antibody Syndrome/Indian J Anesth Analg. 2022;9(3):141-143.
 

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Received Accepted Published
April 12, 2022 May 03, 2022 June 20, 2022
DOI: https://doi.org/10.21088/ijaa.2349.8471.9322.14

Keywords

Pregnancy;APLA.

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Timeline

Received April 12, 2022
Accepted May 03, 2022
Published June 20, 2022

licence

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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