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Case Report

Papillary Tumor of Pineal Region: Clinical Manifestations, Histopathological Insights, and Immunohistochemical Profile: A Comprehensive Case Report

Avinash Singh, , Bharti S1 , Singh A2 , Guralarasan G3 , Bhadani PP4 , Kumari M5

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Indian Journal of Pathology: Research and Practice 13(3):p 111-114, July- September 2024. | DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.13324.4

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Bharti S, Singh A, Guralarasan G et al. Papillary Tumor of Pineal Region: Clinical Manifestations, Histopathological Insights, and Immunohistochemical Profile: A Comprehensive Case Report. Ind Jr of Path: Res and Practice 2024;13(3)111-114.
 


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Abstract

Introduction: Papillary tumor of the pineal region (PTPR) is a unique rare neuroepithelial tumor arising from unique ependymocytes of the subcommissural organ, different from the pineal gland Affecting less than 1% of adult intracranial tumors, PTPR presented unique diagnostic challenges due to rarely and because of its nature papillary pattern does. Case presentation: We report a 25-year-old man initially treated for acute hydrocephalus and later diagnosed with PTPR. Radiologic examination revealed a typical pineal area mass, and histopathology examination confirmed PTPR with prominent papillary structures. Immunohistochemistry played an important role in supporting the disease. Conclusion: This article outlines a complex approach to the diagnosis of PTPR, including radiology, histopathology, and immunohistochemistry. Furthermore, it highlights the uniqueness of PTPR in pineal-parenchymal tumor classification, as outlined in the WHO classification for 2021. This report contributes to the paucity of literature on this rare tumor, and highlights comprehensive diagnostic approach when evaluating pineal region masses


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Bharti S, Singh A, Guralarasan G et al. Papillary Tumor of Pineal Region: Clinical Manifestations, Histopathological Insights, and Immunohistochemical Profile: A Comprehensive Case Report. Ind Jr of Path: Res and Practice 2024;13(3)111-114.
 


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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.13324.4

Keywords

Brain neoplasms; Papillary tumors of the pineal region; Pineal parenchymal tumor.

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