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Myasthenia Gravis: an Autoimmune Neuromuscular Disorder

Mrigshira Tripathi. , Mrigshira Tripathi1 , Sachin C Narwadiya2

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RFP Journal of Biochemistry and Biophysics 5(1):p 19-22, January – June 2020. | DOI:

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Mrigshira Tripathi, Sachin C. Narwadiya. Myasthenia Gravis: an Autoimmune Neuromuscular Disorder. RFP Journal of Biochemistry and Biophysics. 2020;5(1):19–22.
 

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

Myasthenia gravis (MG) is an autoimmune disease which is caused by impaired transmission of signalsat neuromuscular junction and results in problem with muscle contraction. At neuromuscular junction neurotransmitter acetylcholine is released by nerve ends which binds to the receptor at surface of muscle cells. The patients with MG the acetylcholine receptors are blocked or destroyed or altered by its own antibodies and interrupts the communication between nerve cells and muscle cells. MG includes symptoms like weaken muscles, tiredness by any regular work e.g. chopping vegetables, movement of eye, drooping of eyelids and double vision. MG is classified in five types out of which the two main forms are ocular and generalized myasthenia gravis.
Diagnosis and treatment of MG can be done by various process. MG preferably affects young women on their20s and 30s and old men after their 60s.


Keywords: Acetylcholine; Autoimmune disease; Myasthenia gravis; Neuromuscular junction.
 

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Mrigshira Tripathi, Sachin C. Narwadiya. Myasthenia Gravis: an Autoimmune Neuromuscular Disorder. RFP Journal of Biochemistry and Biophysics. 2020;5(1):19–22.
 

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