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Morphological Spectrum of Fine Needle Aspiration Cytology Findings of Breast Lesions With Histopathology Correlation

Jahnavi Marachapu

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Indian Journal of Pathology: Research and Practice 12(2):p 65-72, April-June 2023. | DOI: https://doi.org/10.21088/ijprp.2278.148X.12223.3

How Cite This Article:

Jahnavi Marachapu/Morphological Spectrum of Fine Needle Aspiration Cytology Findings of Breast Lesions With Histopathology Correlation/Indian Journal of Pathology: Research and Practice 2023;12(2) 65–72.

Timeline

Received : February 04, 2023         Accepted : February 22, 2023          Published : June 30, 2023

Abstract

Background: The presence of a breast lump is a prevalent issue that can affect individuals of all ages, from adolescence to old age. The lump can range in severity from benign to malignant. Among the malignant tumours that affect females, breast carcinoma is a leading cause of death worldwide. An early and correct diagnosis of a breast lump is crucial for saving a person's life. In resource limited settings, managing breast lumps can be a difficult task. Materials and Methods: The results obtained from FNAC of palpable breast lumps examined at our department's FNAC from January 2020 to December 2022 were collected and compared to the findings from the excisional biopsies of the same lumps. Result: A total of 325 patients had FNAC of breast lumps during the 2 years period, among which 276 were females and 49 were males. Fine needle Aspiration cytology was performed on 325 cases, and out of these, 270 cases were received in the department for histopathological examination. Out of the total of 325 cases of fine needle aspiration, benign cases were 284 (87.38%), malignant and suspicious were 33 (10.15%) and 8 (1.54%), respectively. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the present study were 98.36%, 96.77%, 91.84%, 91.84%, and 97.27%, respectively. Conclusion: FNAC is a vital initial diagnostic test for palpable breast lumps. The results of breast FNACs are highly comparable to the histology of excisional biopsies, and when performed by an experienced pathologist, it is extremely valuable in managing breast lumps. FNAC is a safe, straightforward, and cost-effective outpatient procedure that is associated with minimal complications. When used in conjunction with histopathological correlation, it improves diagnostic accuracy, which enables physicians to make an early diagnosis and provide specific treatment, thus reducing morbidity and mortality.


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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Jahnavi Marachapu/Morphological Spectrum of Fine Needle Aspiration Cytology Findings of Breast Lesions With Histopathology Correlation/Indian Journal of Pathology: Research and Practice 2023;12(2) 65–72.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
February 04, 2023 February 22, 2023 June 30, 2023

DOI: https://doi.org/10.21088/ijprp.2278.148X.12223.3

Keywords

Fine needle aspiration cytologyFibroadenomaMalignantHistopathology

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Received February 04, 2023
Accepted February 22, 2023
Published June 30, 2023

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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