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Morphological Characterisation of Capillary Hemangioma Pattern: An Indian Study

Vaibhav Jansale Nayak* , Vaibhav Jansale Nayak* , Chatura Kasimsetty Ramakantha**

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Indian Journal of Pathology: Research and Practice 6(1):p 135-141, January - March 2017. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6117.23

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Abstract

 Context: Capillary hemangiomas are fairly common benign tumors encountered across all age groups.Even though they consist of number of clinicopathologically distinct entities, clinicians and pathologists alike have traditionally tended to lump these tumors, under overly generic terms like capillary hemangioma which do little to guide proper clinical management. Aims: To delineate various lesions with capillary hemangioma pattern and outline the morphological features that distinguish each of them. Results: We characterised a collection of 93 cases with capillary hemangioma pattern received over a period of 60 months. Mast cells were counted in 10 fields of high density and mast cell density per square millimetre area was calculated. Statistical Analysis: Pearson correlation coefficient was used to analyse the relationship between mast cell numbers and the age of the lesion. Conclusions: Pathogenesis of capillary hemangiomas remains a hot topic receiving widespread attention of researchers. For a pathologist to distinguish a lobular capillary hemangioma from an Infantile hemangioma or a congenital hemangioma based on morphology is important, pointing to a need for looking beyond using a generic term of capillary hemangioma, and study of a large cohort of cases.

Keywords: Congenital Hemangioma; Epithelioid Hemangioma; Infantile Hemangioma; Lobular Capillary Hemangioma.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6117.23

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