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Is Thrombocytopenia an Alarm for Severe Preeclampsia

Sakshi Thakur, Third year PG, Department of Obstetrics and Gynaecology, Pt. Jawahar Lal Nehru Memorial Medical College and Dr. Bhim Rao Ambedkar Memorial Hospital, Raipur, Chhattisgarh 492001, India , Singh A.1 , Kishore R.2 , Thakur S.3

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Indian Journal of Obstetrics and Gynecology 6(4):p 386-391, July - August 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijog.2321.1636.6418.8

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Abstract

Background: Hypertension is the most common medical problem encountered in pregnancy resulting into alteration of hematological profile, most common of which is thrombocytopenia. The present study is conducted to assess whether platelet count can predict severe forms of HDP and fetomaternal outcome.

Methods: An observational study was conducted in the Department of Obstetrics and Gynaecology at Pt. J.N.M Medical College Dr. BRAMH, Raipur from May 2016 to July 2017. A total of 100 women in their third trimester of pregnancy were investigated. They were divided in two groups on the basis of platelet count and followed till delivery. The mode of delivery, gestational age at the time of delivery and fetomaternal complications were noted. The data collected was tabulated and analyzed.

Results: A significant association was found between severity of HDP and thrombocytopenia p=(.003). Women of HDP with thrombocytopenia had significantly higher number of pretermbirth (p<0.001). Similarly higher number of complications were noted like HELLP(16%), abruption (16%), pulmonary edema (16%), renal failure (11.1%) and PPH (27%) in women with thrombocytopenia. The mean duration of pregnancy was reduced in women with thrombocytopenia (34.57 weeks) as compared to women with normal platelet count (36.36 weeks). The women with thrombocytopenia had more number of fetal complications. 44% had IUGR, 11.1% had IUD and 88% of neonates required NICU admission.

Conclusion: A simple test of platelet count which is cost effective, rapid and accurate can be used in in assessing severity of HDP and timely management.

Keywords: HDP; Platelet Count and Fetomaternal Outcome.

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DOI: DOI: http://dx.doi.org/10.21088/ijog.2321.1636.6418.8

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