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Impact of Repeat-CT on Doses to Target Coverage, Parotid Volume and Organs at Risk During Course of Radiotherapy in Head and Neck Cancer

Virender Bhandari , Sumit Gupta1 , Jayeeta Sen2 , Amresh Kumar3 , Ridhima Ojha4 , Saurabh Karnawat5 , Virender Bhandari6

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Indian Journal of Cancer Education and Research 9(1):p 41-46, January-June 2021. | DOI: http://dx.doi.org/10.21088/ijcer.2321.9815.9121.5

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Sumit Gupta, Jayeeta Sen, Amresh Kumar et al./Impact of Repeat-CT on Doses to Target Coverage, Parotid Volume and Organs at Risk During Course of Radiotherapy in Head and Neck Cancer./ Indian J Canc Educ Res 2021;9(1):41-46.

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Abstract

Head and neck cancer is one of the most common malignancies in India. IMRT technique results in better sparing of OAR and homogenous dose distribution to the target. Adaptive radiotherapy is another step forward in that direction. We did a repeat CT scan during the radiotherapy treatment course followed by recontouring and replanning which resulted in better coverage to PTV and resulted decreased dose to OARs. In our study we found that mean difference between CTV and PTV volumes between Actual Plan and Hybrid Plan is 69.95 (p value 0.001) and 109.24(0.001) respectively. There was a significant reduction in doses received by both parotids. Right parotidgland received 3.03 Gy less in actual plan as compared to hybrid plan and Left parotid gland showed difference of 1.97 Gy between both the plans. Also, the D mean in right Eye was in AP 15.38 ± 10.56 and that of HP19.34 ± 11.27 with a mean difference of 3.96 (p value = 0.001); left eye, the D mean dose with AP 14.43 ± 9.15 and that in HP 18.33 ± 10.24 with a mean difference 3.89 ( p value=0.001).

Keywords: Head and neck cancer; Adaptive radiotherapy; IMRT.

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Sumit Gupta, Jayeeta Sen, Amresh Kumar et al./Impact of Repeat-CT on Doses to Target Coverage, Parotid Volume and Organs at Risk During Course of Radiotherapy in Head and Neck Cancer./ Indian J Canc Educ Res 2021;9(1):41-46.

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DOI: http://dx.doi.org/10.21088/ijcer.2321.9815.9121.5

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