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Histopathological Study and P53 Expression of Colonic PolypsHistopathological Study and P53 Expression of Colonic Polyps

Pernati Mahendranath, Associate Professor, Dept. of Pathology, ACS Medical College & Hospital, Chennai, Tamil Nadu 600077, India. , Vidhya Subramanian1 , Pernati Mahendranath2

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Indian Journal of Pathology: Research and Practice 7(8):p 938-942, August 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7818.10

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Abstract

Background: Hyperplastic and Adenomatous polyps are most common in large intestine. Morphological study of polyps helps us to know the incidence and malignant transformation of polyps.

Aims and Objectives: To study the incidence and morphology of colonic Polyps.

Materials and Methods: Prospective study, 52 colonic polyps were reported which include both colonoscopic biopsies (polypectomy) and resection specimens.

Observation and Results: The commonest site of involvement was sigmoid colon and the commonest lesion was adenomatous polyps.

Conclusion: Adenomatous polyps are more common in colon and further study are required to know the malignant transformation.

Keywords: FAP-Familial Adenomatous Polyposis; PJ Polyp-Peutz-Jeghers Polyp.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7818.10

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