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Indian Journal of Pathology: Research and Practice

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Histopathological Pattern Analysis in Non Neoplastic Skin Biopsies: A Prospective Study of 142 Cases

Manjunath H.K., Professor, Department of Pathology, BGS Global Institute of Medical Sciences, Bengaluru - 560060, Karnataka. , Bhargavi Mohana , Manjunatha H.K.b , Geethamani V.c , Sushma T.A.d , Thejaswini M.U.e , Thej M.J.f

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Indian Journal of Pathology: Research and Practice 7(3):p 299-303, March 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7318.1

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Abstract

Background: Non neoplastic skin lesions form the majority of morbidity from skin diseases, however majority of them are often diagnosed as non specific dermatitis. The objective of this study was to analyse and classify non neoplastic skin lesions based on histopathological pattern and to study the relative frequency of various lesions along with age and sex distribution. Materials and methods: This was a prospective study comprising of 142 cases; from March 2016 to February 2017, done at BGS Global Institute of Medical Sciences. Routine staining with H&E and special stains and Immunofluorescence, wherever needed, were performed. Microscopic findings were studied by two pathologists independently. Results: A total of 142 cases were studied of which papulosquamous disorders (38 %) were the most common lesions followed by dermatitis (27%) and pigment disorders (14%). Conclusion:The high frequency of non specific dermatitis as a final diagnosis may reflect the common reaction pattern of many skin lesions; however detailed evaluation of skin lesions and a pattern based classification, can reduce the frequency of nonspecific diagnosis.

Keywords: Skin Lesions; Non Neoplastic; Histopathology. 

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7318.1

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