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Indian Journal of Pathology: Research and Practice

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FNAC of Lymphadenitides with Granulomatous Lesions Proved to be Belonging to Intriguing Entities on Histopathological Studies

B. Rajashekar Reddy, Associate Professor, Department of Pathology, Mediciti Institute of Medical Sciences, Medchal, Medak, Telangana. , B. Rajashekar Reddy* , Madhavi** , Shirin Damera*** , V.K. Kumar**** , Ranveer Singh*****

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Indian Journal of Pathology: Research and Practice 6(3(part-1)):p 663-667, Jul-Sep 2017. | DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6317.27

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Abstract

Aim: Aim of the study is to review the cytomorphology of granulomatous lymphadenitis on FNAC and confirm with the final histological diagnosis in available cases. Materials and Methods: A retrospective study of 40 cases in a tertiary referral hospital, Mediciti Institute of Medical Sciences, was done for a one year period, i.e., from June 2015 to May 2016. Result: 6 cases out of 40 underwent surgery. 3 cases confirmed the original FNAC diagnosis of granulomatous lymphadenitis. The other 3 cases were diagnosed as metastatic squamous cell carcinoma, anaplastic large cell lymphoma and diffuse large cell lymphoma respectively. Conclusion: A significant number of cases of FNAC diagnosed as granulomatous lymphadenitis have an identifiable underlying causal pathology. FNAC combined with clinical correlation is the first line investigation that helps to single out those that need further investigation or biopsy. use of additional special stain like ZN stain for AFB and culture for AFB in addition to routine H&E. Use of appropriate stains like PAP stain in suspected metastatic carcinoma and Leishman stain in suspected lymphoma can aid in the diagnosis.

Keywords: Granulomatous Lymphadenitis; FNAC; Carcinoma; Lymphoma. 

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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6317.27

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