Home > Journals > Indian Journal of Pathology: Research and Practice

Indian Journal of Pathology: Research and Practice

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Fine Needle Aspiration Cytology of Palpable Breast Lumps with Histologic Correlation: A Two-Year Review

Parakh Priyanka , Parakh Priyanka1 , Mathur Asha

Author Information

Licence:



Indian Journal of Pathology: Research and Practice 8(1):p 83-90, Jun-Feb 2019. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8119.13

How Cite This Article:

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

 Aims: To determine the histopathologic correlation of breast FNAC. Settings and Design: This is a two-year prospective study of breast lumps seen at Department of Pathology, Dr. S.N. Medical College, Jodhpur (Rajasthan) between June 2011 and June 2013. Methods and Material: A total of 526 FNAC cases were evaluated. Histologic follow up was available for 173 FNAC samples. Statistical analysis used: The cytological diagnoses were categorised into one of five diagnostic categories in accordance with the National Health Services Breast Screening Programme of Britain classification (C1, C2, C3, C4, & C5). Then cytological findings were correlated with histological findings and accuracy was assessed by calculating sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, predictive valve, false negative, false positive rates and accuracy. Results: Between June 2011 to June 2013 a total of approximately 526 FNAC breast cases were evaluated. Histologic follow up was available for 173 FNAC samples. Amongst all the cases (526) reported in cytology, maximum cases i.e., 417 (79.28%) cases had C2 lesions. Out of 526 FNAC cases, 173 were correlated in histology. So, in total there were 3 false positive cases and 4 false negative cases in this study. Results calculated were: sensitivity= 89.47%, specificity= 97.78%, positive predictive value= 91.89%, negative predictive value= 97.06% and accuracy= 95.95% Conclusions: A high sensitivity and a high positive predictive value proved that a positive FNAC in the breast means a definite diagnosis of the concerned pathology when compared with the final histology report. The high specificity and a high negative predictive value for malignancy illustrated the high accuracy of FNAC in the diagnosis of malignancy in the breast.

Keywords: FNAC; Histopathology; Correlation; Sensitivity; Accuracy.

References

No records found.


About this article

Cite this article

Licence:



Received Accepted Published
N/A N/A N/A
DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8119.13

Keywords


Article Level Metrics

Last Updated

Sunday 12 July 2026, 13:52:04 (IST)

2018

Accesses

2
434
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share