Home > Journals > Ophthalmology and Allied Sciences

Ophthalmology and Allied Sciences

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Evaluation and Documentation of Ophthalmic Lesions in Children Having Homozygous Sickle Cell Disease

Patel Shivani Dineshkumar , Kapadia Priti Rameshbhai1 , Patel Parth Atulkumar2 , Patel Shivani Dinesh Kumar3

Author Information

Licence:



Ophthalmology and Allied Sciences 5(3):p 279-284, Sep-Dec 2019. | DOI: DOI: http://dx.doi.org/10.21088/oas.2454.7816.5319.5

How Cite This Article:

Kapadia Priti Rameshbhai, Patel Parth Atulkumar, Patel Shivani Dineshkumar. Evaluation and Documentation of Ophthalmic Lesions in Children Having Homozygous Sickle Cell Disease. Ophthalmol Allied Sci. 2019;5(3):279–284

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Background: Homozygous sickle cell disease is prevalent in tribal population of South Gujarat. Aim: To determine prevalence of different ocular manifestations in pediatric patients with homozygous sickle cell disease in South Gujarat. Setting and Design: Cross sectional study at tertiary level government hospital and primary health centers. Methods: 125 children with homozygous sickle cell disease, who fulfilled the criteria were enrolled, were enrolled in the study during a period from December 2015 to June 2017. We collected data on demography, ocular history, hospitalization history and complete eye examination. We calculated systemic severity index. Statistical analysis used: We used SPSS version 20. p value ≤ 0.05 was considered to be statistically significant. Results: Majority of children were from age group 11–18 years (68.8%) and belonged to schedule tribe with almost equal gender distribution; M: F = 1:1.08. Ocular abnormalities were observed in 43 (34.4%) patients. Anterior segment presentations were: Conjuctival sign-21 (16.8%), Iris atrophy-1 (0.8%). Posterior segment signs were: Retinal venous tortuosity-25 (20%), High cup: Disc ratio-3 (2.4%), Vitreous hemorrhage (Grade 4 Proliferative Central Retinopathy) -4 patients (3.2%), Salmon patch hemorrhage-2 (1.6%), Angioid streaks-2 (1.6%), Drusen-1 (0.8%), Central retinal artery occlusion-1 (0.8%). Ocular manifestations were found to be statistically significant in patients with systemic severity index between 0.8- 1. Blindness was found in 4% cases. Conclusion: Mild ocular morbidities are found in children having homozygous sickle cell disease in most vulnerable communities of South Gujarat. Regular eye check-up is recommended in children having high systemic severity index for early diagnosis and treatment of potential blinding conditions.

Keywords: Homozygous sickle cell disease; Systemic severity index; Venous tortuosity; Conjuctival sickling sign; Vitreous hemorrhage.

References

No records found.


About this article

Cite this article

Kapadia Priti Rameshbhai, Patel Parth Atulkumar, Patel Shivani Dineshkumar. Evaluation and Documentation of Ophthalmic Lesions in Children Having Homozygous Sickle Cell Disease. Ophthalmol Allied Sci. 2019;5(3):279–284

Licence:



Received Accepted Published
N/A N/A N/A
DOI: DOI: http://dx.doi.org/10.21088/oas.2454.7816.5319.5

Keywords


Article Level Metrics

Last Updated

Sunday 26 July 2026, 12:30:02 (IST)

579

Accesses

2
66
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share