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Effect of Low Dose Magnesium Sulphate on Succinylcholine Induced Fasciculations & Postoperative Myalgia

Gajendra Singh, Associate Professor, Department of Anesthesia, Mahadevappa Rampure Medical College, Sedam Road, Kalaburagi, Karnataka 585105, India. , Nanda S Nandyal1 , Gajendra Singh2 , Kaja Sriramamurthy3

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Indian Journal of Anesthesia and Analgesia 6(1):p 77-80, Jan-Feb 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6119.10

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Nanda S Nandyal, Gajendra Singh, Kaja Sriramamurthy. Effect of Low Dose Magnesium Sulphate on Succinylcholine Induced Fasciculations & Postoperative Myalgia. Indian J Anesth Analg. 2019;6(1):77-80.

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Abstract

Objectives: To investigate the effect of Magnesium Sulphate on Succinylcholine induced fasciculations during General Anaesthesia & postoperative myalgia. Methods: Double blind randomised clinical trial on patients who were candidates for surgery under general anaesthesia. Patients were selected & divided into two equal groups of Study & controls using block randomisation. Study group received Magnesium Sulphate while Controls received Normal Saline. SPSS 18 was used for statistical analysis. Results: Out of the 100 subjects in the study 49 (49%) were men & 51 (51%) were women (p<0.072). The mean age of the two groups were 37.5±12.2 year & 37.7±12 year (p<0.9). There was significant difference between the two groups in terms of the degree of fasciculations & post operative myalgia (p<0.001). Conclusion: Even low dose of magnesium sulphate can prevent & reduce the degree of succinylcholine induced fasciculation & postoperative myalgia. 

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Nanda S Nandyal, Gajendra Singh, Kaja Sriramamurthy. Effect of Low Dose Magnesium Sulphate on Succinylcholine Induced Fasciculations & Postoperative Myalgia. Indian J Anesth Analg. 2019;6(1):77-80.

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6119.10

Keywords

Magnesium sulphate; muscle fasciculation; succinylcholine; Postoperative Myalgia (POM)

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