Home > Journals > Journal of Cardiovascular Medicine and Surgery

Journal of Cardiovascular Medicine and Surgery

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

During Extracorporeal Circulation (ECC): Metabolic Characteristics Management Reduce Post Operative Sepsis, Liver Dysfunction and Renal Dysfunction in Paediatric Patients

Ramesh Patel, Professor, Department of Cardiac Anesthesia, U.N.Mehta institute of cardiology and research centre. Ahmedabad, Gujarat 380016, India. , Solanki Atul* , Patel Ramesh** , Acharya Himanshu*** , Patel Jignesh**** , Sharma Jainam*****

Author Information

Licence:



Journal of Cardiovascular Medicine and Surgery 3(2):p 102-109, Jul-Dec 2017. | DOI: http://dx.doi.org/10.21088/jcms.2454.7123.3217.4

How Cite This Article:

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Aim: Aim of this study is to investigate the impact of perfusion flow, haematocrit level, lactate level and DO2 (oxygen delivery) during extracorporeal circulation for paediatric patients post operative sepsis, liver and renal dysfunctions. Introduction: Organ dysfunction afterextracorporeal circulation (ECC) has been associated with oxygen delivery DO2. For conventional extracorporeal circuit required crystalloid priming solution of 350450 ml, resulting in hemodilution.The metabolic needs of paediatric patients during ECC is organ specific because of tissues oxygen consumption VO2. If the ratio of VO2/DO2 is increase during ECC in paediatric patients which give unreliable value of VO2/DO2.This unreliable values give an anaerobic metabolism and lactic acidosis. Due to hemodilution and low delivery of oxygen, postoperative morbidity and mortality will increase. Material and Methods: In this prospective study we enrolled total of 180 consecutive paediatric and small children. Who underwent for cardiac surgery with extracorporeal circulation system. Patients were divided into two groups, based on patients haematocrit level ï‚£ 8.5% and >8.5% haematocrit level, oxygen delivery (DO2) and extracorporeal circulation pump flow were recorded. For all paediatric operation with extracorporeal circulate system patients preoperative and postoperativetotal blood count, platelet count, blood urea, serum creatinine, electrolytes, SGPT, SGOT and total bilirubin(tb), serological viral test HepatitisB (HBsAg) and HIV test were performed. Result: In this prospective study we have investigated the lowest haematocrit, lowest oxygen delivery DO2, and low perfusion flow rates may increase postoperative sepsis, liver dysfunction, renal dysfunction and overall ventilation hours / ICCU stay. Conclusion: The present study explored the specific haematocrit level, oxygen delivery DO2 level, perfusion flow and lactate level during ECC in paediatric patients postoperative sepsis, liver dysfunction, renal dysfunction and overall ventilation hours / ICCU stay. The low haematocrit level and low perfusion flow during ECC in paediatric patients is a possible risk for post operative renal dysfunction. Adequate oxygen delivery and perfusionflow reduced risk of renal dysfunction and liver dysfunction.

 

References

No records found.


About this article

Cite this article

Licence:



Received Accepted Published
N/A N/A N/A
DOI: http://dx.doi.org/10.21088/jcms.2454.7123.3217.4

Keywords

Extracorporeal; Haematocrit; Liver; Renal. 

Article Level Metrics

Last Updated

Monday 22 June 2026, 12:25:23 (IST)

681

Accesses

1
121
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share