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Dosimetric Comparison of 3DCRT Planning and Forward IMRT Field in Field Techniques in Early Stage Left Breast Cancer

Chinnamuthu Mahendran null, Chinnamuthu Mahendran1 null, Ganapathi Murugan2 null, Anmol Verma3 null, Saurabh Karnawat4 null, Virendra Bhandari5 null

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Indian Journal of Cancer Education and Research 10(1):p 17-25, January - June 2022. | DOI: https://doi.org/10.21088/ijcer.2321.9815.10122.2

How Cite This Article:

Chinnamuthu Mahendran, Ganapathi Murugan, Anmol Verma, et. al./Dosimetric Comparison of 3DCRT Planning and Forward IMRT Field in Field Techniques in Early Stage Left Breast Cancer/Indian J Canc Educ Res 2022;10(1):17-25.


Timeline

Received : November 20, 2021         Accepted : December 03, 2021          Published : June 10, 2022

Abstract

Background: The objective of the study is to compare Forwarded IMRT FiF plan with Enhance Dynamic Wedge (EDW) tangential field radiotherapy in terms of dosimetric benefits for OARs early stage left side breast cancer radiotherapy. Materials and Methods: Twenty patients of consecutive left side breast cancer who underwent breast conserving surgery were included and without surgery patients were also included in the study. Two different methods of treatment plans were created for the entire left side breast cancer patients. Forwarded IMRT Field in Field plans (FiF) plan and Enhance Dynamic Wedge (EDW) planning’s are compared for doses in the planning target volume (PTV), the organs at risk (OARs) volume including ipsilateral lung, heart, left ascending coronary artery (LAD) and the contralateral breast, the dose homogeneity index (DHI), conformity index (CI) and the monitor units (MUs) counts required for the treatment. Results: The homogeneity conformity of the dose to planning target volume (PTV) and the dose delivered to the heart, contralateral breast, and left ascending coronary artery (LAD) were compared with two techniques in all the 20 patients. Both the radiotherapy techniques achieved comparable radiation dose delivery to PTV-95% of the prescribed dose covering > 95% of the breast PTV as well as the mean doses of the heart, ipsilateral lung, contralateral lung, aorta, left atrium, right atrium, left ventricle, right ventricle, contralateral breast. Forwarded IMRT FiF technique achieving better uniform dose distribution and conformity with lower doses to OARs and less MUs. Conclusion: The Forwarded IMRT FiF technique achieving better dose distribution in the PTV and spare the OARs. The lesser MUs required for treatment of the Forwarded IMRT FiF technique seems to be more advantageous compared to the Enhance Dynamic Wedge plan during whole left side breast irradiation


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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Chinnamuthu Mahendran, Ganapathi Murugan, Anmol Verma, et. al./Dosimetric Comparison of 3DCRT Planning and Forward IMRT Field in Field Techniques in Early Stage Left Breast Cancer/Indian J Canc Educ Res 2022;10(1):17-25.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
November 20, 2021 December 03, 2021 June 10, 2022

DOI: https://doi.org/10.21088/ijcer.2321.9815.10122.2

Keywords

Breast cancerEnhanced dynamic wedgeDose volume histograms;Intensity modulated radiotherapyField in field techniqueAn organ at riskMonitor units.

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Received November 20, 2021
Accepted December 03, 2021
Published June 10, 2022

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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