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Indian Journal of Anesthesia and Analgesia

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Dexmedetomidine an Adjuvant in Anaesthesia for Functional Endoscopic Sinus Surgery (FESS)

Vijayarekha Koti, Associate Professor, Department of Anaesthesiology, Deccan College of Medical Sciences, Hyderabad, Telangana 500058. , Vijayarekha Koti* , Sharathbabu Chevuri* , Syed Abdul Wasiq** , Bashirunnisa**

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Indian Journal of Anesthesia and Analgesia 4(2):p 532-536, April - June 2017. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4217.28

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Abstract

Introduction: Dexmedetomidine can provide controlled hypotension, analgesia, and sedation. The present study aimed to evaluate advantages of dexmedetomidine as an adjuvant in anesthesia fo FESS (Functional Endoscopic Sinus Surgery). Materials and Methods: Study was conducted in 50 patients form April-2015 to March -2016 after obtaining approval from ethical committee and informed consent from the patients. who were ASA grade I/II, aged between 18-55years scheduled for FESS. Patients were randomly allocated into two groups of Group D (n=25) which received injection Dexmeditomidine as loading dose of 1 mcg/kg intravenously followed by maintenance infusion of 0.6mcg/kg intravenously and Group NS (n=25) received normal saline in similar volume. Results: The baseline mean systolic blood pressure was lower during surgery in patients of group D, but not statistically significant . At the end of surgery and after recovery, blood pressure is significantly lower in group D (114± 11 vs. 131 ± 9 mmHg; P < 0.05). Baseline values of the mean heart rate intraoperatively was significantly reduced compared with the baseline value in group D (P < 0.05), After extubation, the heart rate was found to be higher in patients of the GroupNS (98 ± 4 vs. 86 ± 3 beats/ minutes). Blood losses were lower in group D as compared to group NS ( p= 0.03 ).The Visual Analogue Scale (VAS) scores in the immediate postoperative periods were also significantly lower in the group D ( p =0.03 ). The only side effect noted was bradycardia in 3 patients in group D. Isoflurane requirement was also reduced in the maintenance of anaesthesia. Conclusion: Dexmedetomidine as an adjuvant for hypotensive anaesthesia is effective and decreases bleeding thus providing relatively bloodless field during FESS.

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4217.28

Keywords

Sinusitis; D e x m e d e t o m i d i n e ; Hypotensive Effect; Anesthesia Adjuvants.

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