Aspin R Professor, SCPM College of Nursing and Paramedical Sciences, Gonda, Haripur 271003, Uttar Pradesh, India
M. Mayelu Professor, SCPM College of Nursing and Paramedical Sciences, Gonda, Haripur 271003, Uttar Pradesh, India
S. Balachandar Professor, SCPM College of Nursing and Paramedical Sciences, Gonda, Haripur 271003, Uttar Pradesh, India
Address for correspondence: Aspin R, Professor, SCPM College of Nursing and Paramedical Sciences, Gonda, Haripur 271003, Uttar Pradesh, India E-mail: dr.aspin.r@gmail.com
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator
M. Mayelu, Aspin R, S. Balachandar/Delayed Cord Clamping: A Review of Benefits and Risks/Indian J Obstet Gynecol. 2023;11(3):109–113.
Timeline
Received : July 19, 2023
Accepted : August 07, 2023
Published : September 30, 2023
Abstract
The yolk sac and the allantois give rise to and are preserved in the umbilical cord. By the fifth week of development, it has formed and is the embryo's new source of nutrition, taking the place of the yolk sac. The cord joins the placenta, which transports substances to and from the mother's blood without allowing them to directly mix, rather than being directly attached to the mother's circulatory system. The umbilical cord can be clamped at various times, although postponing it until at least one minute after delivery improves results, provided that the minor risk of jaundice can be treated if it does occur. Clamping is followed by a painless cord cutting procedure because there are no nerves present. Out of those 20 studies, only 5 studies discuss the risk associated with delayed cord clamping, 2 studies discuss the benefit associated with good nutritional status, 2 studies discuss the benefit associated with good neurodevelopment, and the remaining studies discuss the increase in hemoglobin due to delayed cord clamping.
References
1. Meyer WW, Rumpelt HJ, Yao AC, Lind J. Structure and closure mechanism of the human umbilical artery. Eur J Pediatr. 1978;128:247–59.
2. Sujatha R. Cultural practices and beliefs on newborn care among mothers in a selected hospital of Mangalore taluk. Journal of Health and Allied Sciences NU. 2014;4 (02):21–6.
3. McDonald SJ, Middleton P, Dowswell T, Morris PS. Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes. Evid Based Child Health. 2014;9(2):303–97.
4. Shukla A. Clinical evaluation of delayed cord clamping in outcome in preterm babies admitted in district female hospital, Basti, Uttar Pradesh.
5. Rana N, Kc A, Målqvist M, Subedi K, Andersson O. Effect of delayed cord clamping of term babies on neurodevelopment at 12 months: a randomized controlled trial. Neonatology. 2019;115(1):36–42.
6. Ashish KC, Rana N, Målqvist M, Ranneberg LJ, Subedi K, Andersson O. Effects of delayed umbilical cord clamping vs early clamping on anemia in infants at 8 and 12 months: a randomized clinical trial. JAMA Pediatr. 2017;171(3):264–70.
7. Hutton EK, Hassan ES. Late vs early clamping of the umbilical cord in full-term neonates: systematic review and meta-analysis of controlled trials. JAMA. 2007;297 (11):1241–52.
8. Rabe H, Reynolds GJ, Diaz Rosello JL. Early versus delayed umbilical cord clamping in preterm infants. Cochrane Database of Systematic Reviews. 2004;(4).
9. Rabe H, Jewison A, Alvarez RF, Crook D, Stilton D, Bradley R, et al. Milking compared with delayed cord clamping to increase placental transfusion in preterm neonates: a randomized controlled trial. Obstetrics & Gynecology. 2011;117(2 Part 1):205–11.
10. Krueger MS, Eyal FG, Peevy KJ, Hamm CR, Whitehurst RM, Lewis DF. Delayed cord clamping with and without cord stripping: a prospective randomized trial of preterm neonates. Am J Obstet Gynecol. 2015;212(3):394-e1.
11. Rich D. Delayed cord clamping: A multidisciplinary Approach. Journal of Obstetric, Gynecologic, & Neonatal Nursing. 2015;44(s1):S9–10.
12. Kc A, Singhal N, Gautam J, Rana N, Andersson O. Effect of early versus delayed cord clamping in neonate on heart rate, breathing and oxygen saturation during first 10 minutes of birthrandomized clinical trial. Matern Health Neonatol Perinatol. 2019;5(1):1–7.
13. Duley L, Dorling J, Pushpa-Rajah A, Oddie SJ, Yoxall CW, Schoonakker B, et al. Randomised trial of cord clamping and initial stabilisation at very preterm birth. Archives of Disease in ChildhoodFetal and Neonatal Edition. 2018;103(1):F6–14.
14. Patel S, Clark EAS, Rodriguez CE, Metz TD, Abbaszadeh M, Yoder BA. Effect of umbilical cord milking on morbidity and survival in extremely low gestational age neonates. Am J Obstet Gynecol. 2014;211(5):519-e1.
15. Mercer JS, Erickson-Owens DA, Collins J, Barcelos MO, Parker AB, Padbury JF. Effects of delayed cord clamping on residual placental blood volume, hemoglobin and bilirubin levels in term infants: a randomized controlled trial. Journal of Perinatology. 2017;37(3):260–4.
16. Chaparro CM, Neufeld LM, Alavez GT, Cedillo REL, Dewey KG. Effect of timing of umbilical cord clamping on iron status in Mexican infants: A randomised controlled trial. The Lancet. 2006;367(9527):1997–2004.
17. McDonald SJ, Middleton P, Dowswell T, Morris PS. Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes. Evid Based Child Health. 2014;9(2):303–97.
18. Katheria AC, Brown MK, Faksh A, Hassen KO, Rich W, Lazarus D, et al. Delayed cord clamping in newborns born at term at risk for resuscitation: a feasibility randomized clinical trial. J Pediatr. 2017;187:313–7.
19. Andersson O, Lindquist B, Lindgren M, Stjernqvist K, Domellöf M, Hellström-Westas L. Effect of delayed cord clamping on neurodevelopment at 4 years of age: a randomized clinical trial. JAMA Pediatr. 2015;169(7):631–8.
20. Kaempf JW, Tomlinson MW, Kaempf AJ, Wu Y, Wang L, Tipping N, et al. Delayed umbilical cord clamping in premature neonates. Obstetrics & Gynecology. 2012;120(2 Part 1): 325–30.
21. Brocato B, Holliday N, Whitehurst Jr RM, Lewis D, Varner S. Delayed cord clamping in preterm neonates: a review of benefits and risks. Obstet Gynecol Surv. 2016;71 (1):39–42.
22. Fogarty M, Osborn DA, Askie L, Seidler AL, Hunter K, Lui K, et al. Delayed vs early umbilical cord clamping for preterm infants: a systematic review and meta-analysis. Am J Obstet Gynecol. 2018;218(1):1–18.
23. Shinohara E, Kataoka Y. Prevalence and risk factors for hyperbilirubinemia among newborns from a low risk birth setting using delayed cord clamping in Japan. Japan Journal of Nursing Science. 2021;18(1):e12372.
24. Vural I, Ozdemir H, Teker G, Yoldemir T, Bilgen H, Ozek E. Delayed cord clamping in term large forgestational age infants: A prospective randomised study. J Paediatr Child Health. 2019;55(5):555–60.
Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
About this article
Cite this article
M. Mayelu, Aspin R, S. Balachandar/Delayed Cord Clamping: A Review of Benefits and Risks/Indian J Obstet Gynecol. 2023;11(3):109–113.
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator
This license enables
reusers to distribute, remix, adapt, and build upon the material in any medium
or format for noncommercial purposes only, and only so long as attribution is
given to the creator