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Cytological and Histomorphological Correlation of Salivary Gland Lesions: Study at a Rural Tertiary Healthcare Hospital

C.R. Sirajunnisa Begum, Associate Professor, Department of Pathology, Apollo Medical College, Murukambattu, Chittoor, Andhra Pradesh 517217, India. , Govindaraj T.* , C.R. Sirajunnisa Begum** , Kalla Raviteja***

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Indian Journal of Pathology: Research and Practice 6(4 (Part-2)):p 1024-1028, Oct-Dec 2017. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6417.33

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Aim/Objective: The objective of this study was to evaluate the diagnostic accuracy of FNAC in various salivary gland lesions and it’s correlation with histopathology, which helps in the appropriate management of the patient. Materials and Methods: A total of 65 FNA were performed on salivary gland lesion from September 2016 to August 2017 at department of pathology of a Tertiary care centre. Surgically resected, formalin fixed specimen were received, they were processed and slides were prepared. The cytological and histopathological stained slides were studied, analysed and correlated clinically. Results: The cytological features of 65 cases were studied and following lesions were observed in FNAC study of 65 cases: 28 were pleomorphic adenomas (43%), 15 were of chronic sialadenitis (23%), 4 were Warthin’s tumours (6%), 4 were mucoepidermoid carcinomas (6%), 4 were benign parotid tumour( 6%), 2(3%)were carcinoma ex pleomorphic adenomas, 2 were metastatic deposits(3%), 4 were cystic lesions (6%) and 2 were malignant tumours (3%)(unclassified). The sensitivity, specificity, positive predictive value and negative predictive value of present study is 78.5%, 75%, 72.4%, 91.6%, 40.9% respectively. Conclusion: FNAC of the salivary gland is a safe and reliable technique in the primary diagnosis of salivary gland lesions. Though the rate of characterization of specific type of tumor is lower, due to variable cytomorphology in case of FNAC, histopathological examination may prove to be accurate and gold standard for diagnosis. This study implies that FNAC of the salivary gland tumours is safe, simple, rapid and costeffective diagnostic method for the patient.

Keywords: FNAC; Sensitivity; Specificity; Cytology; Histopathology. 

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6417.33

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