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Correlation of Imprint, Scrape and Crush Cytology with Conventional Histopathology in Diagnosis of Benign and Malignant Lesions

Adlekha Shashikant* , Adlekha Shashikant* , Chadha Tandra**

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Indian Journal of Pathology: Research and Practice 6(1):p 57-62, January - March 2017. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6117.9

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Abstract

 Background: Cytological tools, imprint and crush smear techniques are simple and rapid techniques in diagnosis of various lesions. Aims and Objectives: 1. To evaluate the utility of imprint, scrape and crush cytology as diagnostic modality. 2. To study the advantages and limitations of cytological techniques. 3) To correlate, compare and contrast with histopathology examination. Material and Methods: A prospective study, comprising of 200 cases of various specimen, submitted in histopathology department. Smears by different cytological techniques were stained by rapid H&E , PAP stain and Giemsa stains. Results: Imprint and crush smears showed cent percent diagnostic accuracy in diagnosing CNS lesion, Genitourinary, Bone, Testis and skin and soft tissue lesions. Lesions from Breast, Gastrointestinal lesions, Tumor resection margins , also showed high diagnostic concordance between cytological methods and histopathological examination. Conclusion: Imprint, scrape and crush smear methods are rapid cost effective techniques of obtaining accurate diagnosis of benign and malignant lesions.

Keywords: Imprint Cytology; Crush Cytology; Scrape Cytology; Histopathoogy.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.6117.9

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