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Correlation between Human Epidermal Growth Factor Receptor and Hormonal Receptor Status with Grade and Nodal Status in Carcinoma Breast: A Prospective Observational Study

Rohit Krishnappa, Assistant Professor, Department of General Surgery, Rajarajeswari Medical College and Hospital, Kambipura, Mysore Road, Bangalore, Karnataka, India 560074. , Manjunath Ka , Rohit Krishnappaa , Raksha Ravikumarb , S. Rajagopalanc

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New Indian Journal of Surgery 8(3):p 364-367, Jul-Sep 2017. | DOI: https://dx.doi.org/10.21088/nijs.0976.4747.8317.11

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Abstract

Breast carcinoma is the most common malignant tumor and the leading cause of carcinoma death in women. Tissue evaluation gives information about various receptors which are yield prognostic information for further treatment. Identification of clinically predictive and prognostic factors is considered as an important issue in treatment of breast cancer. There are a number of tumor related features available to predict the prognosis of breast cancer. The involvement of axillary lymph nodes (ALNs) is the most important prognostic factor in operable primary breast cancer. In our study we try to find out the correlation between human epidermal growth factor Receptor (HER-2/neu) and hormonal receptor status (Estrogen/Progesterone ER,PR) with grade and nodal status in carcinoma breast.

 

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DOI: https://dx.doi.org/10.21088/nijs.0976.4747.8317.11

Keywords

Carcinoma Breast; Human Epidermal Growth Factor; Estrogen/Progesterone Receptors; Axillary Lymph Node; Sentinel Node Biopsy. 

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