Home > Journals > Ophthalmology and Allied Sciences

Ophthalmology and Allied Sciences

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Correlation between Altered Serum Lipid Profile and Spectral Domain Optical Coherence Tomography based Macular Thickness Parameters in Diabetic Retinopathy

Sandeep Saxena , Sandeep Saxena , Shivani Sinha , Khushboo Srivastav , Vinod K. B. M.

Author Information

Licence:



Ophthalmology and Allied Sciences 1(1):p 7-13, January - June 2015. | DOI:

How Cite This Article:

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Aim: To study the correlation between altered serum lipid profile and spectral domain optical coherence tomography (SD-OCT) based macular thickness parameters in diabetic retinopathy. Method: Study subjects included 60 cases of type 2diabetes mellitus (DM): no diabetic retinopathy (No DR, n=20); non proliferative DR (NPDR, n=20); proliferative DR (PDR, n=20) and 20 healthy controls. Best corrected visual acuity (BCVA) was measured on logMAR scale. Cube average thickness (CAT) and central subfield thickness (CST) was assessed using SD-OCT. Serum lipid profile was analyzed using standard protocol. Data was analyzed statistically. Result: Decrease in BCVA positively correlated with increased CAT (r=0.25, p=0.028), increased CST (r=0.28, p=0.04), increased serum cholesterol (r=292, p=0.01) and decreased high density lipoprotein (r=-0.714, p=0.01). Statistically significant positive correlation was found between increase in CAT with increase in serum cholesterol (r=0.403, p=0.00) and also with increase in low density lipoprotein (r=0.343, p=0.02.). Conclusion: Deranged lipid profile correlates with the progression of diabetic retinopathy. Further, this study demonstrates the correlation of deranged lipid profile and decreased visual acuity with increased CAT.

Keywords: Diabetic Retinopathy; Lipid Profile; Spectral Domain Optical Coherence Tomography; Cube Average Thickness; Central Subfield Thickness. 

References

No records found.


About this article

Cite this article

Licence:



Received Accepted Published
N/A N/A N/A
DOI:

Keywords


Article Level Metrics

Last Updated

Wednesday 24 June 2026, 10:31:16 (IST)

393

Accesses

5
66
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share