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Ophthalmology and Allied Sciences 4(3):p 235-240, Sep-Dec 2018. | DOI: DOI: http://dx.doi.org/10.21088/oas.2454.7816.4318.8
Original Article
Corneal Endothelial Cell Characteristics, Central Corneal Thickness and Its Relationship to Age in Normal South Indian Eyes
Rajani Kadri, Associate Professor, Department of Ophthalmology, A.J. Institute of Medical Sciences, Mangalore, Karnataka 575004, India. , DOI: http://dx.doi.org/10.21088/oas.2454.7816.4318.8
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Ophthalmology and Allied Sciences 4(3):p 235-240, Sep-Dec 2018. | DOI: DOI: http://dx.doi.org/10.21088/oas.2454.7816.4318.8
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Abstract
Aim: The aim of this study was to discuss the corneal endothelial cell characteristics, central corneal thickness and determine the relationship with age.
Methods: 200 eyes of 100 patients underwent specular microscopy. Corneal Endothelial Cell Density (CECD), Mean Cell Area (MCA), percentage of hexagonal cells, Coefficient of variation
(CV) and Central Corneal Thickness (CCT) were the parameters collected.
Results: Mean CECD was 2675.8±384.4 cells/mm2. MCA (Mean cell area) was 387.79 µm2±91.27 µm2, Coefficient of variation (CV) in cell size was 37.440 %±8.395% and percentage of regular hexagonal cells was 49.870%±7.921%. There was a statistically significant inverse correlation between age and CECD. A positive correlation was observed between CV, MCA and age.
Conclusion: CECD and CCT decreases with age. MCA and CV increase with age. Percentage of regular hexagonal cells is not dependent on age.
Keywords: Central Corneal Thickness; Corneal Endothelial Cell; Specular Microscopy.
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DOI: DOI: http://dx.doi.org/10.21088/oas.2454.7816.4318.8
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