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Comparison of Single Dose of Cefotaxime Versus Multiple Doses of Cefotaxime and Metrogyl as Antibiotic Prophylaxis in Elective Caesarian Section

Chandrika Kanne. , Chandrika Kanne1 , Venkateswara Rao Jakamsetti2 , Purnima Jyothi Kondapaneni3

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Indian Journal of Obstetrics and Gynecology 8(3):p 125-130, July–September 2020. | DOI: http://dx.doi.org/10.21088/ijog.2321.1636.8320.2

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Chandrika Kanne, Venkateswara Rao Jakamsetti, Purnima Jyothi Kondapaneni.Comparison of Single Dose of Cefotaxime
Versus Multiple Doses of Cefotaxime and Metrogyl as Antibiotic Prophylaxis in Elective Caesarian Section, Indian J Obstet Gynecol.
2020;8(3):125–130.
 


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Received : N/A         Accepted : N/A          Published : N/A

Abstract

Background: Evaluation of fetal well being ismajor concern in obstetrics especially in high risk pregnancy. Fetal monitoring is based on a diagnosticprocedure, among which Doppler sonographyhas become a top-level non-invasive method.Uterine Doppler evaluation predicts most of theoccurrences of the early-onset preeclampsia andintrauterine growth restriction, and its use in thesepregnancies will improve the perinatal outcomes. Doppler investigation of middle cerebral artery in
combination with umbilical artery seems toimprove the early prediction of adverse perinatal outcome in high risk pregnancies.


Method: 100 pregnant women with high risk factors (pre-Eclampsia, IUGR and GDM) after 34 weeks till term were evaluated for their colour Doppler findings and the perinatal outcome was analysed.


Results: UA PI had high specificity and low sensitivity for adverse perinatal outcome. MCA RI had highest sensitivity, MCA PI had highest
specificity. Ratio of MCA/Umibilical artery PI has highest specificity than independent vessel Doppler. All Doppler indices were highly specific in diagnosing abnormal perinatal outcome with comparatively low
sensitivity.


Conclusions: Adverse fetal outcome has been seen to be associated with abnormal Doppler finding. Thus prompt diagnosis of impaired feto-placental circulation in form of abnormal Doppler guides us forappropriate fetal surveillance and timely termination in high risk pregnancy. 
 


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Cite this article

Chandrika Kanne, Venkateswara Rao Jakamsetti, Purnima Jyothi Kondapaneni.Comparison of Single Dose of Cefotaxime
Versus Multiple Doses of Cefotaxime and Metrogyl as Antibiotic Prophylaxis in Elective Caesarian Section, Indian J Obstet Gynecol.
2020;8(3):125–130.
 


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DOI: http://dx.doi.org/10.21088/ijog.2321.1636.8320.2

Keywords

Umbilical artery doppler; MCADoppler; sensitivity; prematurity.

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