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Comparison of Optical Coherence Tomography and Humphrey Visual Field in Early Glaucoma Diagnosis: Observational Study

K. Kanthamani, Professor and Head, Department of Ophthalmology, Sri Devaraj Urs Medical College, Kolar, Karnataka 563101, India. , Usha B.R.1 , K. Kanthamani2 , Meghana C. Reddy3 , Nithiya J. Babu4

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Ophthalmology and Allied Sciences 4(2):p 154-159, May - August 2018. | DOI: DOI: http://dx.doi.org/10.21088/oas.2454.7816.4218.19

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Abstract

 Objective: To study the diagnostic accuracy of Retinal nerve fibre layer (RNFL) thickness and perimetric field defects in early diagnosis of Primary open angle glaucoma(POAG). Materials and Methods: Eyes fulfilling inclusion criteria were selected for this study from ophthalmology glaucoma clinic outpatient department at R.L. Jalappa Hospital. Informed consent was take from all patients. They were divided

into 3 groups. Group I consists of 23 glaucoma suspect eyes.Group II consists of 23 eyes with early glaucoma. Group III consists of 23 normal eyes. Each patient underwent best corrected visual acuity (BCVA), Intraocular pressure (IOP) estimation, slit lamp examination, fundus examination particularly for Cup Disc ratio (C/D), gonioscopy, Optical Coherence Tomography (spectral) and Humphrey Visual Field (HVF) - 750. Superior, inferior, nasal, temporal, average RFNL thickness compared among all
groups. Mean deviation (MD) and pattern standard deviation (PSD) of Humphrey visual field analysis statistically comparedwith RFNL thickness. Statistical analysis was made by ANOVA test. Results: The mean intra ocular pressure was 18.9mmHg, 21.56mmHg, 12.0mmHg in group I, II, III respectively. The mean C/D ratio was 0.90, 0.98, 0.4 in these three consecutive groups. Average RNFL thickness was 94.2microns, 72.33 microns, 112.23microns in three consecutive groups. The mean of mean deviation
(MD) and the mean of pattern standard deviation (PSD) in group I showed -0.73 and 1.70 respectively. The mean MD and the mean PSD in group II showed -3.58 and 9.20 respectively. The mean MD and the mean PSD in group III showed -0.215 and 1.272 respectively. Conclusion: OCT is superior in diagnosis of glaucoma particularly in suspect groups. RNFL thickness measured by OCT discriminates better between glaucomatous, glaucoma suspect and normal eyes. 
 
Keywords: OCP; HFA

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DOI: DOI: http://dx.doi.org/10.21088/oas.2454.7816.4218.19

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