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Comparison of Epidural Levobupivacaine 0.125% with Fentanyl 2 mcg/ ml and evobupivacaine 0.125% Alone for Postoperative Pain Management

Krishna Patel, Senior Resident, Department of Anaesthesia, MGM Medical College, Kamothe, Navi Mumbai, Maharashtra 410209, India. , Olvyna D’souza1 , Krishna Patel2 , Manish Kokne3

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Indian Journal of Anesthesia and Analgesia 6(1):p 19-26, Jan-Feb 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6119.2

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Abstract

Introduction: The aim of the study was to compare effectiveness of single dose epidural 0.125% levobupivacaine with fentanyl 2 mcg/ml and 0.125% levobupivacaine alone in patients undergoing elective lower limb orthopaedic surgery. Methodology: We designed a prospective, randomized, double blind study, in which 60 patients with ASA1 and ASA2 were scheduled to undergo elective lower limb orthopedic surgery. Group A received single epidural block with 8 ml of 0.125% levobupivacaine and Group B received epidural block with 8 ml of 0.125% levobupivacaine and 2 mcg/ml fentanyl. Duration of analgesia, Quality of analgesia,  Degree of motor blockade, sedation score, hemodynamic changes and side effects were
assessed. Results: Duration of postoperative analgesia for group B (366±39.70 min) was longer as compared to group A (236±34.99 min). Quality of anaesthesia was significantly better in group B as compared Group A. Conclusion: We conclude that addition of fentanyl 2 mcg/ml to epidural 0.125% levobupivacaine produces significantly better quality and longer duration of postoperative analgesia, good hemodynamic stability and no side effect as compared to 0.125% levobupivacainealone in patient undergoing elective lower limb orthopedic surgeries.

 

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6119.2

Keywords

Keywords: Levobupivacaine; Fentanyl; Postoperative Pain. 

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