Home > Journals > Indian Journal of Anesthesia and Analgesia

Indian Journal of Anesthesia and Analgesia

Submit your article Read this Journals View all journals
Full Text (PDF)
Original Article

Sevoflurane Induction of Anaesthesia in Critically ill Patients Undergoing Emergency Laparotomy

Ajai Vikram Singh , Satyendra Yadav1 , Ajai Vikram Singh2 , Harun Ali3

Author Information

Licence:



Indian Journal of Anesthesia and Analgesia 6(1):p 9-18, Jan-Feb 2019. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6119.1

How Cite This Article:

Timeline

Received : N/A         Accepted : N/A          Published : N/A

Abstract

Sevoflurane has characteristics of rapid inhalational induction of anaesthesia in 60 secs while maintaining spontaneous respiration, bronchodilatation, haemodynamic stability with rapid recovery in elective scenario. This retrospective study analysed 40 (n=40) critically ill patients undergoing induction of anaesthesia with sevoflurane in emergency laparotomy. Standard methods and techniques were used in patient induction and management. Patients were optimized prior to sevoflurane induction were in ASA-III E (72.5%) and ASA-IV E (27.5%) status. Clinical outcome of sevoflurane anaesthesia induction analysed in terms of any airway managment complication and haemodynamic stability. Statistical analysis of haemodynamics done by ANOVA (analysis of variance). Incidence of airway complication such as laryngospasm, aspiration were nil and none of patient required abandoning or modification in induction process. Patients Spo2 improved postinduction (only 2.5% SpO2 between 85%-90%) even in comorbid COPD and smoker patients showing beneficial effects of sevoflurane induction. Induction of anaesthesia with sevoflurane is associated with significant changes (p < .05) in MAP and pulse peaking at 3 minutes postinduction as sevoflurane induction unable to attenuate intubation response on haemodynamics. None of the patient had bradycardia (HR < 60 bpm), hypotension (MAP < 60 mmHg) and arryythemias or required additional vasopressor support post induction and throughout perioperative period. None of patient required postoperative ventilation due to delayed recovery. Study concludes sevoflurane induction is without airway complications and haemodynamic unstability is suitable induction agent in emergency laparotomy in optimized critically ill patients while taking measure to prevent aspiration though unable to inhibit adrenergic endotracheal intubation responses.

References

No records found.


About this article

Cite this article

Licence:



Received Accepted Published
N/A N/A N/A
DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6119.1

Keywords

Sevoflurane; Induction of Anaesthesia; Emergency Laparotomy; Haemodynamic stability; Airway complications; safety; Critical patients.

Article Level Metrics

Last Updated

Monday 13 July 2026, 12:28:39 (IST)

5653

Accesses

5
678
00

Citations


NA
NA
NA

Download citation


Article Keywords

Keyword Highlighting

Highlight selected keywords in the article text.


Timeline

Received N/A
Accepted N/A
Published N/A

licence




Access this article

Reprint Order Form
Buy this Article
Institutional Subscriptions

Share