V. Haribabu Assistant Professor, Department of Anaesthesia, Chengalpattu Medical College, Chengalpattu 603001, Tamil Nadu, India
S. Subramaniam Associate Professor, Department of Anaesthesia, Government Arignar Anna Memorial Cancer Hospital, Kanchipuram, Tamil Nadu 631552, India
Address for correspondence: S. Subramaniam, Associate Professor, Department of Anaesthesia, Government Arignar Anna Memorial Cancer Hospital, Kanchipuram, Tamil Nadu 631552, India E-mail: ckdubbi@gmail.com
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Haribabu V, Subramaniam S. Comparison of effects of levobupivacaine vs ropivacaine vs bupivacaine in phacoemulsion surgeries of oncology cases: a randomised controlled trial. Ind J Anesth Analg. 2025;12(3):177-181.
Timeline
Received : March 21, 2025
Accepted : June 05, 2025
Published : September 11, 2025
Abstract
Objective: To evaluate the efficacy and to compare the quality of peribulbar block anaesthesia of 0.5% Levobupivacaine, 0.5% Ropivacaine and 0.5% Bupivacaine for cataract surgery in post surgical/ post chemotheraphy/ post radiotheraphy oncology cases.
Place and Duration of Study: Chengalpattu Medical College, Chengalpattu. 2023 - 24.
Study Design: Randomized Controlled Clinical Trial.
Methodology: After obtaining approval from institutional ethics committee and written informed consent from all patients, a randomized controlled double blinded clinical trial was conducted on 30 ASA 3 oncology patients undergoing cataract surgery. Patients were randomly allocated into three groups. Group L, Group R and Group B of 10 each. Patients in Group L were to receive Levobupivacaine 0.5%, Group R 0.5% Ropivacaine and Group B 0.5% Bupivacaine. Haemodynamic variables (heart rate, systolic and diastolic BP) and the onset and duration of sensory and motor block, sensory regression time, Intraocular Pressure values were recorded and compared using ANOVA test.
Conclusion: Levobupivacaine is better suited for phacoemulsion surgeries of Post Surgical/ post chemotheraphy/ post radiotheraphy oncology cases.
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Data Sharing Statement
There are no additional data available.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
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Conflicts of Interest
The authors report no conflicts of interest in this work.
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Haribabu V, Subramaniam S. Comparison of effects of levobupivacaine vs ropivacaine vs bupivacaine in phacoemulsion surgeries of oncology cases: a randomised controlled trial. Ind J Anesth Analg. 2025;12(3):177-181.
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.