Mahesh KM , Chiranthkumar G Nelogal , Ramachandraiah R. , Mahesh KM , Satish Kumar MN , Sudheesh K.
Chiranthkumar G Nelogal, Ramachandraiah R, Mahesh KM, et al. Comparision of Effects of Fentanyl and Intravenous
Paracetamol on Consumption of Sevoflurane. Indian J Anesth Analg. 2020;7(3):726–733.
Aims: The study was designed to compare the effect of IVFentanyl vs. IV Paracetamol on consumption of
Sevoflurane and the recovery characteristics.
Plan of study: Patients scheduled for elective surgeries under
general Anaesthesia are randomly allocated with 50 patients in each group. Group- F received Fentanyl
1mcg/kg per min as bolus 5min before infusion immediately after intubation. Group- P received Paracetamol
1gm in 100ml for a period of 15min and twenty five minutes before intubation. Intra-operatively Sevoflurane
concentration was titrated to maintain entropy value of 40-60. Total volume of Sevoflurane consumed
is obtained from GE/Datex-Omeda S/5 advance monitor and average Sevoflurane consumed in ml/hr is
calculated.
Results: Consumption of Sevoflurane in Group- F was 16.01 ± 0.95ml/hr as compared to 16.9 ± 2.2
ml/hr in Group- P which was statistically significant. Post extubation at the end of fifth minute all patients in
Group- P attained score of 12 as compared to only 56% patients of Group- F and it was is statistica lly significant
(p <0.001).
Conclusion: Consumption of Sevoflurane & post-operative pain was less in Fentanyl group when
compared to paracetamol group. However recovery characteristics are better in paracetamol group.
No records found.
Chiranthkumar G Nelogal, Ramachandraiah R, Mahesh KM, et al. Comparision of Effects of Fentanyl and Intravenous
Paracetamol on Consumption of Sevoflurane. Indian J Anesth Analg. 2020;7(3):726–733.
| Received | Accepted | Published |
|---|---|---|
| N/A | N/A | N/A |
Tuesday 14 July 2026, 09:06:25 (IST)
Download citation
Highlight selected keywords in the article text.
| Received | N/A |
| Accepted | N/A |
| Published | N/A |