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Intravenous Dexamethasone As Adjuvant to Axillary Brachial Plexus Blockade For Forearm Orthopedic Surgeries: A Randomized Controlled Trial

Shankara Narayana P , Dhananjaya Kumar SM , Shankara Narayana P.

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Indian Journal of Anesthesia and Analgesia 7(3):p 734-738, May-June 2020. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.7320.12

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Dhananjaya Kumar SM, Shankara Narayana P. Intravenous Dexamethasone As Adjuvant to Axillary Brachial Plexus Blockade
For Forearm Orthopedic Surgeries: A Randomized Controlled Trial. Indian J Anesth Analg. 2020;7(3):734–738


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Abstract

Introduction: perineural dexamethasone prolongs the duration of a single injection peripheral nerve block when added to the local anesthetic solution while perineural use of dexamethasone remains off-label. Postulated systemic mechanisms of action along with safety concerns have prompted the investigation of intravenous dexamethasone as an alternative.

Aim: We aimed to confirm that the addition of intravenous dexamethasone will prolong the duration of analgesia after a single-shot axillary brachial plexus block compared to conventional long-acting local anesthetic alone.

Material And Method: 46 Asa I to III adult patients scheduled for elective forearm and hand surgeries were randomly allocated to 2 groups of 23 patients each. Patients in group D received axillary brachial plexus block with an injection of 30 ml bupivacaine 0.5% and 2 ml of dexamethasone (8mg) IV and Patients in control group A received axillary brachial plexus block with an injection of 30 ml of bupivacaine 0.5% and 2ml of 0.9% saline IV prior to surgery.

Results: There was a statistically significant difference in the duration of post-operative analgesia, duration of motor and sensory blockade, and better overall patient satisfaction in group D when compared to group A.

Conclusion: We concluded that a Single axillary brachial plexus block with 0.5% bupivacaine and intravenous dexamethasone resulted in prolonged duration of postoperative analgesia, sensory and motor blockade, and better patient satisfaction


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Cite this article

 

Dhananjaya Kumar SM, Shankara Narayana P. Intravenous Dexamethasone As Adjuvant to Axillary Brachial Plexus Blockade
For Forearm Orthopedic Surgeries: A Randomized Controlled Trial. Indian J Anesth Analg. 2020;7(3):734–738


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Received Accepted Published
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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.7320.12

Keywords

Intravenous dexamethasoneBrachial plexus blockAxillary brachial plexus block.

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