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Comparative Study of Pap Smear Versus Visual Inspection with Acetic Acid (Via) and Lugol’s Iodine (VILI) in Screening of Cervical Cancer

, Swetha O.N. , Sneha Rajiv

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Indian Journal of Obstetrics and Gynecology 5(3 (Supplement)):p 278-278, Jul-Sep 2017. | DOI:

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Aims and Objectives: To compare VIA and VILI with Pap smear examination, to establish VIA and VILI as an alternate method for cervical cancer screening. And to establish the diagnostic accuracy of VIA and VILI directed biopsy in abnormal Pap smears and VIA, VILI positive lesions. Methods: It is a Prospective study of 250 Women Who meet inclusion criteria, in the age group of 21- 65years. All underwent PAP smear, VIA and VILI examination.Cervical biopsy taken from cases positive for any of the three tests and histhopathological evaluation done.Sensitivity, specificity, PPV, NPV calculated for each test and Compared. Results: Among 250 patients, 17 were positive for PAP smear, 37 were positive for VIA, 31 were positive for VILI. Total of 46 biopsies were taken, among them 19 were positive on histopathological examination. Four cases were missed by PAP smear, 5 cases were missed by VIA and 6 cases were missed by VILI examination. Conclusion: VIA and VILI can be used as an alternative to PAP smear examination in the screening of cervical cancer in a low resource setting. 


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