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Indian Journal of Anesthesia and Analgesia

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Comparative Evaluation of Intrathecal Dexmedetomidine with Fentanyl as an Adjuvant to Hyperbaric Bupivacaine in Lower-Limb Orthopaedic Surgeries

Priyadarshini M. Bentur, W/o Dr. A.R. Veeresh, # 175, 3rd Main, P.J. Extension, Davangere – 577 002. , Bentur Priyadarshini M.* , Hanji Anitha S.* , Baig Javeedullah**

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Indian Journal of Anesthesia and Analgesia 4(2):p 477-482, April - June 2017. | DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4217.19

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Abstract

Background: Spinal anesthesia is an age old, tested, effective and economical technique of regional anaesthesia especially for lower-limb orthopaedic surgeries because of its excellent muscle relaxation and intraoperative and postoperative analgesia profile. Aims: To compare the efficacy of adjuvants dexmedetomidine and fentanyl when added to intrathecal bupivacaine. Setting & Design: 120 patients were enrolled in the study. They were randomly allocated into dexmedetomidine group (BD) and fentanyl group (BF) and received 5 µg dexmedetomidine and 25 µg fentanyl respectively as adjuvants  to 2.5 ml intrathecal bupivacaine. Materials & Methods: Both group BD and BF were compared with respect to age, sex, weight, height, time to onset of maximum motor blockade (Bromage 4 ), maximum level of sensory level achieved, intraoperative VAS score, hemodynamic, postoperative VAS score, time to two – segment regression, time to regression to S2 level and regression to Bromage 0 were noted. Statistical Analysis: Unpaired t-test and ch i- square test were used. Conclusion & Results: Significant difference was found between both groups with BD group having prolonged time to regression in two-segment and S1 level and Bromage - 0 postoperative VAS scores were lesser with BD group.

 

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.4217.19

Keywords

Intrathecal Dexmedetomidine; Intrathecal Fentanyl; Hyperbaric Bupivacaine; Orthopedic Surgeries.

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