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Clinicopathological Study of Primary Epithelial Malignant Tumours of Thyroid Gland in a Tertiary Care Centre, Kolar

Dr Manjula K., Associate Professor, Dept. of Pathology, Sri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka 563101, India. , Pradeep Mitra V.1 , Manjula K.2 , CSBR Prasad3

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Indian Journal of Pathology: Research and Practice 7(6):p 792-796, June 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7618.15

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Abstract

Clinicopathological study of primary epithelial malignant tumours of thyroid gland: in a tertiary care centre, Kolar. Introduction Thyroid malignancy is the most common malignancy in endocrine system accounting for 87% of all endocrine gland tumors [1]. The incidence of thyroid cancers has been in the rising in the past two decades. The increase in incidence may be due to early detection of asymptomatic cases through screening tests [2,3]. These epithelial tumors are characterized by unique clinical, molecular and biological features [2,4]. Hence it is important to know the different histomorphology of these tumors to foresee prognosis and guide the treatment for better outcome.

Materials and methods: The study was conducted in the department of Pathology, Sri Devaraj Urs Medical College, Kolar constituent college Sri Devaraj Urs Academy of higher education and Research. All the primary malignant epithelial thyroid carcinoma cases were retrieved from the archives of Pathology from January 2010 to December 2016 for the duration of 7 years.

Results: Total numbers of primary epithelial malignancies were 62 cases (2.5% of all malignant cases). The most common thyroid malignancy was the papillary carcinoma (54 cases, 87%) Conclusions Primary epithelial tumors of thyroid accounted to 100% of thyroid malignancy. Most patients presented with neck mass. Papillary carcinoma accounted to 87% of epithelial carcinoma, more common in females. Anaplastic and follicular carcinoma was seen in older age, were associated with distant metastasis 

Keywords: Malignant Epithelial Tumors; Papillary Carcinoma; Medullary Carcinoma;
Vascular Invasion.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7618.15

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